Importance Obesity affects approximately 42% of US adults and is associated with increased
rates of type 2 diabetes, hypertension, cardiovascular disease, sleep disorders …

Fatty acid metabolism is known to support tumorigenesis and disease progression as well
as treatment resistance through enhanced lipid synthesis, storage and catabolism. More …

Despite the substantial gains in our understanding of NAFLD/NASH over the past 2
decades, there has been some dissatisfaction with the terminology “non‐alcoholic” which …

Obesity must be considered a real pathology. In the world wide, obesity represent one of the
major public health issue associated with increased morbidity and mortality. Overweight or …

Conclusions This study demonstrates that E. multilocularis can induce T‐cell exhaustion
through inhibitory receptor TIGIT, and that blocking this checkpoint may reverse the …

Obesity is the most extended metabolic alteration worldwide increasing the risk for the
development of cardiometabolic alterations such as type 2 diabetes, hypertension, and …

The prevalence of obesity is a major cause of many chronic metabolic disorders, including
type 2 diabetes mellitus (T2DM), cardiovascular disease (CVD), and cancer. Insulin …

Although obesity is associated with numerous diseases, the risks of disease may depend on
metabolic health. Associations between the gut microbiota, obesity, and metabolic syndrome …

Abdominal and general adiposity are independently associated with mortality, but there is
no consensus on how best to assess abdominal adiposity. We compared the ability of …

Importance Improved understanding of trends in the proportion of individuals with
metabolically healthy obesity (MHO) may facilitate stratification and management of obesity …