This paper reviews available reports on the advantages and possibilities of clinical use of
platelet-rich plasma preparations, with particular emphasis on platelet growth factors …

Objective: Autologous platelet rich plasma is an advanced wound therapy used in hard-to-
heal acute and chronic wounds. To better understand the use and clinical outcomes of the …

The application of blood plasma for soft tissue wound healing is receiving much more
attention recently. Exosomes are critical paracrine mediators that can be obtained from …

We systematically searched available databases. We reviewed 6,143 studies published
from 1833 to 2017. Reports in English, French, German, Italian, and Spanish were …

We present a new video-assisted minimally invasive technique for the treatment of pilonidal
disease (EP Si. T: endoscopic pilonidal sinus treatment). Between March and November …

Pilonidal disease presents many therapeutic challenges to surgeons throughout the world.
Its varied clinical presentations necessitate a wide range of treatments, thus underscoring …

Abstract Background The present German National Guideline is an updated version of
previous Guideline published in 2014. It aims to compare various treatment methods and to …

Abstract The Italian Society of Colorectal Surgery (SICCR.) has prepared clinical practice
guidelines to help its members to optimize the treatment of pilonidal disease, a very common …

Topical treatment with platelet derivatives has increasingly been described as being
capable of accelerating wound healing and to aid in tissue repair. In vitro data indicate that …

Pilonidal sinus disease (PSD) is increasing globally. A recent meta-analysis and merged-
data analysis showed that recurrence rates in PSD depend essentially on follow-up time and …