There are seven relaxin family peptides that are all structurally related to insulin. Relaxin has
many roles in female and male reproduction, as a neuropeptide in the central nervous …

One of the recently emerging topics in biotechnology is natural receptors including G protein-
coupled receptors, ligand-gated ion channels, enzyme-linked receptors, and intracellular …

Neuropeptides and peptide hormones are ancient, widespread signaling molecules that
underpin almost all brain functions. They constitute a broad ligand-receptor network, mainly …

Abstract The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of
the key properties of over 2000 human drug targets with their pharmacology, plus links to an …

The superfamily of G-protein-coupled receptors (GPCRs) could be subclassified into 7
families (A, B, large N-terminal family B-7 transmembrane helix, C, Frizzled/Smoothened …

Relaxin has vital physiological roles in pregnant rats, mice, and pigs. Relaxin promotes
growth and softening of the cervix, thus facilitating rapid delivery of live young. Relaxin also …

GPCR135, publicly known as somatostatin-and angiotensin-like peptide receptor, is
expressed in the central nervous system and its cognate ligand (s) has not been identified …

Certain lower vertebrates like zebrafish activate proliferation of spared cardiomyocytes after
cardiac injury to regenerate lost heart muscle. Here, we used translating ribosome affinity …

G protein–coupled receptors (GPCRs) are major regulators of intercellular interactions. They
initiate these actions by being activated by a wide variety of natural ligands. Historically …

The physiological role of an orphan G protein-coupled receptor, LGR5, was investigated by
targeted deletion of this seven-transmembrane protein containing a large N-terminal …