Polysaccharides in ocular drug delivery

N Dubashynskaya, D Poshina, S Raik, A Urtti… - Pharmaceutics, 2019 - mdpi.com
Polysaccharides, such as cellulose, hyaluronic acid, alginic acid, and chitosan, as well as
polysaccharide derivatives, have been successfully used to augment drug delivery in the …

Injectable hydrogels for ophthalmic applications

K Wang, Z Han - Journal of Controlled Release, 2017 - Elsevier
The demand for effective eye therapies is driving the development of injectable hydrogels as
new medical devices for controlled delivery and filling purposes. This article introduces the …

[HTML][HTML] Carboxymethyl-hexanoyl chitosan: A promising candidate for hydrophobic and hydrophilic drug delivery

BN Kumara, NG Gurudatt, KS Prasad - Carbohydrate Polymer Technologies …, 2023 - Elsevier
Biodegradable polymers are versatile materials that are used in a plethora of biomedical
applications owing to their biocompatible nature, degradability, non-toxicity, and low cost …

Extended release of hyaluronic acid from hydrogel contact lenses for dry eye syndrome

FA Maulvi, TG Soni, DO Shah - Journal of Biomaterials Science …, 2015 - Taylor & Francis
Current dry eye treatment includes delivering comfort enhancing agents to the eye via eye
drops, but low residence time of eye drops leads to low bioavailability. Frequent …

Updates on thermosensitive hydrogel for nasal, ocular and cutaneous delivery

Q Wang, Z Zuo, CKC Cheung, SSY Leung - International Journal of …, 2019 - Elsevier
Thermosensitive hydrogels are in situ gelling systems composed of hydrophilic
homopolymers or block copolymers which remain as solutions at room temperature and …

Glaucoma treatment and hydrogel: Current insights and state of the art

AM Fea, C Novarese, P Caselgrandi, G Boscia - Gels, 2022 - mdpi.com
Aqueous gels formulated using hydrophilic polymers (hydrogels) and those based on stimuli-
responsive polymers (in situ gelling or gel-forming systems) attract increasing interest in the …

Why chitosan could be apt candidate for glaucoma drug delivery-An overview

BN Kumara, R Shambhu, KS Prasad - International Journal of Biological …, 2021 - Elsevier
Most of the people in the world are affected by glaucoma, which leads to irreversible
blindness. Several patient friendly treatments are available, nevertheless medications lack …

Inhibition of periodontitis induction using a stimuli‐responsive hydrogel carrying naringin

PC Chang, YC Chao, MH Hsiao… - Journal of …, 2017 - Wiley Online Library
Background: Developing a drug carrier with favorable handling characteristics that can
respond to environmental changes after inflammation, such as pH changes, may be …

Injectable insulin-lysozyme-loaded nanogels with enzymatically-controlled degradation and release for basal insulin treatment: In vitro characterization and in vivo …

HS Chou, M Larsson, MH Hsiao, YC Chen… - Journal of Controlled …, 2016 - Elsevier
Diabetes is a common global disease that causes immense suffering for individuals and
huge costs for the health care system. To minimize complications such as organ …

Nanomedicine and drug delivery to the retina: Current status and implications for gene therapy

M Tawfik, F Chen, JL Goldberg, BA Sabel - … -schmiedeberg's Archives of …, 2022 - Springer
Blindness affects more than 60 million people worldwide. Retinal disorders, including age-
related macular degeneration (AMD), diabetic retinopathy (DR), and glaucoma, are the …