Bubbles in microfluidics—even those that appear to be negligibly small—are pervasive and
responsible for the failure of many biological and chemical experiments. For instance, they …

Two hybrid back-propagation neural network (BPNN) models optimized by two heuristic
search algorithms, namely genetic algorithm (GA-BP) and particle swarm optimization (PSO …

In recent years, significant progress has been made in the studies of the spring-driven
autoinjector, leading to an improved understanding of this device and its interactions with …

Autoinjectors are becoming a primary drug delivery option to the subcutaneous space.
These devices need to work robustly and autonomously to maximize drug bio-availability …

Purpose Cavitation is an undesired phenomenon that may occur in certain types of
autoinjectors (AIs). Cavitation happens because of rapid changes of pressure in a liquid …

Cavitation, the formation and collapse of vapor-filled bubbles, poses a problem in spring-
driven autoinjectors (AIs). It occurs when the syringe accelerates abruptly during activation …

Understanding the interface motion and hydrodynamic shear induced by the liquid sloshing
during the insertion stage of an autoinjector can help improve drug product administration …

Antineoplastic medication compounding is conducted in most large hospitals and involves
the repetitive task of extracting a specific quantity of medication from vials using syringes …

Abrupt acceleration of the syringe of an autoinjector (AI) upon rod-plunger impact may
induce undesired severe cavitation events and impose extraneous stresses upon the …

This paper presents a model for bubble dynamics in a protein solution, including varying
surface tension and dynamic adsorption/desorption of protein onto the bubble surface. We …