Processed product (Pinelliae Rhizoma Praeparatum) of Pinellia ternata (Thunb.) Breit. Alleviates the allergic airway inflammation of cold phlegm via regulation of PKC …

X Tao, H Liu, J Xia, P Zeng, H Wang, Y Xie… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Pinelliae Rhizoma Praeparatum (PRP) is a
traditional processed product of Pinellia ternata (Thunb.) Berit., which mainly used for …

Best practices in mAb and soluble target assay selection for quantitative modelling and qualitative interpretation

D Fairman, H Tang - The AAPS Journal, 2023 - Springer
Biologics, especially monoclonal antibodies (mAbs), are an increasingly important part of
the drug discovery and development portfolio across the pharmaceutical industry. To enable …

A model‐based approach using GSK3772847, an anti‐interleukin‐33 receptor monoclonal antibody, as a showcase to predict SC administration PK and free target …

J Berkhout, D Fairman, M van Noort… - CPT …, 2025 - Wiley Online Library
Integrated modeling of the pharmacokinetic (PK) and target binding, by means of a TMDD
model, can provide valuable insights into the expected pharmacodynamic (PD) effects of …