The thalamus is a small, bilateral structure in the diencephalon that integrates signals from
many areas of the CNS. This critical anatomical position allows the thalamus to influence …

Cortical networks are composed of glutamatergic excitatory projection neurons and local
GABAergic inhibitory interneurons that gate signal flow and sculpt network dynamics …

We present a unique, extensive, and open synaptic physiology analysis platform and
dataset. Through its application, we reveal principles that relate cell type to synaptic …

Similarities in neocortical circuit organization across areas and species suggest a common
strategy to process diverse types of information, including sensation from diverse modalities …

Neuronal networks with strong recurrent connectivity provide the brain with a powerful
means to perform complex computational tasks. However, high-gain excitatory networks are …

Tactile sensory information from facial whiskers provides nocturnal tunnel-dwelling rodents,
including mice and rats, with important spatial and textural information about their immediate …

The sensory cortex contains a wide array of neuronal types, which are connected together
into complex but partially stereotyped circuits. Sensory stimuli trigger cascades of electrical …

Homeostatic mechanisms stabilize neuronal activity in vivo, but whether this process gives
rise to balanced network dynamics is unknown. Here, we continuously monitored the …

An understanding of the diversity of cortical GABAergic interneurons is critical to understand
the function of the cerebral cortex. Recent data suggest that neurons expressing three …

Cortical processing reflects the interplay of synaptic excitation and synaptic inhibition.
Rapidly accumulating evidence is highlighting the crucial role of inhibition in shaping …