When challenged by a difficult reduction reaction, a chemist should always also consider
biocatalysis in synthesis planning. The inherent selectivity of enzymes has been known for …

The asymmetric bioreduction of alkenes bearing an electron-withdrawing group using flavin-
dependent enzymes from the 'old yellow enzyme'family at the expense of NAD (P) H yields …

Enzyme catalysis, made tremendous progress over the last years in identification of new
enzymes and new enzymatic reactivity's as well as optimization of existing enzymes …

This Minireview highlights the application of crystallization as a very powerful in situ product
removal (ISPR) technique in biocatalytic process design. Special emphasis is placed on its …

Many drug candidate molecules contain at least one chiral centre, and consequently, the
development of biocatalytic strategies to complement existing metal‐and organocatalytic …

The biocatalytic activity of nitroreductase from Salmonella typhimurium (NRSal) was
investigated for the reduction of α, β-unsaturated carbonyl compounds, nitroalkenes, and …

The removal of inhibiting or degrading product from a bioreactor as soon as the product is
formed is an important issue in industrial bioprocess development. In this review, the …

Unfavorable equilibrium positions are often a critical factor in the process development of
biocatalytic reactions and usually require secondary solutions for efficient synthesis …

Bioprocess such as enzymatic reaction and fermentation have experienced fast
development as green and sustainable techniques, which can integrate with different …

This useful reference focuses on the currently available toolbox of bio-catalysed reductions
of C= O, C= C and formal C= N bonds to show which transformations can be reliably used in …