Spheroids provide a 3D environment with intensive cell–cell contacts. As a result of their
excellent regenerative properties and rapid progress in their high-throughput production …

Induced pluripotent stem cells (iPSCs) offer an unprece-dented opportunity to study human
physiology and disease at the cellular level. They also have the potential to be leveraged in …

Clinical translation of cell‐based products is hampered by their limited predictive in vivo
performance. To overcome this hurdle, engineering strategies advocate to fabricate tissue …

The constant supply of high cell numbers generated by defined, robust, and economically
viable culture processes is indispensable for the envisioned application of human …

Over the past two decades, human embryonic stem cells (hESCs) have gained attention due
to their pluripotent and proliferative ability which enables production of almost all cell types …

Aiming at clinical translation, robust directed differentiation of human pluripotent stem cells
(hPSCs), preferentially in chemically defined conditions, is a key requirement. Here …

Human induced pluripotent stem cells (hiPSCs) represent an almost limitless source of cells
for disease modelling and drug screening applications. Here we established an efficient and …

Although tissue engineering using human-induced pluripotent stem cells is a promising
approach for treatment of cardiovascular diseases, some limiting factors include the survival …

Fabrication of appropriate electro-conductive scaffold, application of small molecules (SMs),
electrical stimulation (ES), and stem cells are steps forward in cardiac tissue engineering …

A dual cross-linking strategy was developed to answer the urgent need for fatigue-resistant,
cytocompatible, and in situ forming tough hydrogels. Clickable, yet calcium-binding …