Alterations in the gut microbiota composition have been associated with a range of
neurodevelopmental, neurodegenerative, and neuropsychiatric disorders. The gut microbes …

Variation in the blood metabolome is intimately related to human health. However, few
details are known about the interplay between genetics and the microbiome in explaining …

Introduction As Sub-Saharan Africa (SSA) undergoes rapid urbanization changes in diet and
lifestyle have contributed to a rise in non-communicable diseases (NCDs) across the region …

Mislocalization and abnormal expression of N-methyl-D-aspartate glutamate receptor
(NMDAR) subunits is observed in several brain disorders and pathological conditions …

Increased p-cresol levels reportedly alter brain dopamine metabolism and exacerbate
neurological disorders in experimental animals. In contrast to toxic concentrations, low …

Several studies have highlighted a high comorbidity between epilepsy and autism. We
hypothesized that some similar etiological factors might affect both disorders; among such …

Gastrointestinal illnesses are one of the most common comorbidities reported in patients
with neurodevelopmental diseases, including autism spectrum disorders (ASD). Gut …

The effects of p-cresol on the levels of subunit 2RB of NMDA receptors and also of AMPA
and GABAA receptors in the nucl. accumbens (NAc) of rats were studied. As was found, the …

It is established that p-cresol, a compound produced by bacterial colonies within the
gastrointestinal tract of mammals, plays a contributory role in the manifestation of various …

The article discusses the findings of laboratory experiments conducted over the past seven
years, focusing on the investigation of the brain-gut axis. These experiments examine not …