Natural Products (NP) are essential for the discovery of novel drugs and products for
numerous biotechnological applications. The NP discovery process is expensive and time …

Covering: 1997 to 2023 The shikimate pathway is the metabolic process responsible for the
biosynthesis of the aromatic amino acids phenylalanine, tyrosine, and tryptophan. Seven …

Quantitative activity and species source data of natural products (NPs) are important for drug
discovery, medicinal plant research, and microbial investigations. Activity values of NPs …

Chronic inflammation is a common underlying factor in many major diseases, including
heart disease, diabetes, cancer, and autoimmune disorders, and is responsible for up to …

Highlights•Siderophores/metallophores mediate metal acquisition and host-microbe
interactions.•Genome mining aids metallophore discovery, dereplication, and …

Natural products have been proven to be important starting points for the development of
new drugs. Bacteria in the genera Photorhabdus and Xenorhabdus produce antimicrobial …

Bioinformatics has become an indispensable tool for natural products research in the
genomic era. One of the key challenges is to accurately convert sequence data of a …

The transmission of antibiotic-resistance genes, comprising mobilization and relocation
events, orchestrates the dissemination of antimicrobial resistance. Inspired by this …

Covering: up to March 2024. Microbial natural products have historically been a cornerstone
for the discovery of therapeutic agents. Advanced (meta) genome sequencing technologies …

Genome mining is revolutionizing natural products discovery efforts. The rapid increase in
available genomes demands comprehensive computational platforms to effectively extract …