Cell biology of hyphal growth

G Steinberg, MA Peñalva, M Riquelme… - Microbiology …, 2017 - Am Soc Microbiol
Filamentous fungi are a large and ancient clade of microorganisms that occupy a broad
range of ecological niches. The success of filamentous fungi is largely due to their elongate …

[HTML][HTML] Phenotypic heterogeneity in fungi: importance and methodology

SK Hewitt, DS Foster, PS Dyer, SV Avery - Fungal Biology Reviews, 2016 - Elsevier
Phenotypic heterogeneity describes the variation that exists between individual cells, spores
or other biological entities within genetically-uniform populations of fungi or other organisms …

Functional analysis of the Aspergillus fumigatus kinome identifies a druggable DYRK kinase that regulates septal plugging

N van Rhijn, C Zhao, N Al-Furaiji, ISR Storer… - Nature …, 2024 - nature.com
More than 10 million people suffer from lung diseases caused by the pathogenic fungus
Aspergillus fumigatus. Azole antifungals represent first-line therapeutics for most of these …

Large-scale identification of genes involved in septal pore plugging in multicellular fungi

MAA Mamun, W Cao, S Nakamura… - Nature …, 2023 - nature.com
Multicellular filamentous fungi have septal pores that allow cytoplasmic exchange, and thus
connectivity, between neighboring cells in the filament. Hyphal wounding and other stress …

Intercellular cooperation in a fungal plant pathogen facilitates host colonization

R Peyraud, M Mbengue, A Barbacci… - Proceedings of the …, 2019 - National Acad Sciences
Cooperation is associated with major transitions in evolution such as the emergence of
multicellularity. It is central to the evolution of many complex traits in nature, including growth …

[HTML][HTML] Go with the flow: mechanisms driving water transport during vegetative growth and fruiting

KC Herman, R Bleichrodt - Fungal Biology Reviews, 2022 - Elsevier
Fungi need water for all stages of life. Notably, mushrooms consist of∼ 90% water. Fungi
degrade organic matter by secreting enzymes. These enzymes need water to be able to …

Regulation of fungal decomposition at single-cell level

M Op De Beeck, C Troein, S Siregar, L Gentile… - The ISME …, 2020 - academic.oup.com
Filamentous fungi play a key role as decomposers in Earth's nutrient cycles. In soils,
substrates are heterogeneously distributed in microenvironments. Hence, individual hyphae …

Yeast-to-hypha transition of Schizosaccharomyces japonicus in response to environmental stimuli

C Kinnaer, O Dudin, SG Martin - Molecular biology of the cell, 2019 - Am Soc Cell Biol
Many fungal species are dimorphic, exhibiting both unicellular yeast-like and filamentous
forms. Schizosaccharomyces japonicus, a member of the fission yeast clade, is one such …

Looking outside the box: A comparative cross-kingdom view on the cell biology of the three major lineages of eukaryotic multicellular life

R Panstruga, W Antonin, A Lichius - Cellular and Molecular Life Sciences, 2023 - Springer
Many cell biological facts that can be found in dedicated scientific textbooks are based on
findings originally made in humans and/or other mammals, including respective tissue …

Life as a moving fluid: fate of cytoplasmic macromolecules in dynamic fungal syncytia

M Roper, CH Lee, PC Hickey, AS Gladfelter - Current opinion in …, 2015 - Elsevier
In fungal syncytia dozens, or even millions of nuclei may coexist in a single connected
cytoplasm. Recent discoveries have exposed some of the adaptations that enable fungi to …