Non–cystic fibrosis bronchiectasis

PJ McShane, ET Naureckas, G Tino… - American journal of …, 2013 - atsjournals.org
There is renewed interest in non–cystic fibrosis bronchiectasis, which is a cause of
significant morbidity in adults and can be diagnosed by high-resolution chest computed …

Huanglongbing pandemic: current challenges and emerging management strategies

D Ghosh, S Kokane, BK Savita, P Kumar, AK Sharma… - Plants, 2022 - mdpi.com
Huanglongbing (HLB, aka citrus greening), one of the most devastating diseases of citrus,
has wreaked havoc on the global citrus industry in recent decades. The culprit behind such …

The infant nasopharyngeal microbiome impacts severity of lower respiratory infection and risk of asthma development

SM Teo, D Mok, K Pham, M Kusel, M Serralha, N Troy… - Cell host & …, 2015 - cell.com
The nasopharynx (NP) is a reservoir for microbes associated with acute respiratory
infections (ARIs). Lung inflammation resulting from ARIs during infancy is linked to asthma …

Bacterial microbiota of the upper respiratory tract and childhood asthma

M Depner, MJ Ege, MJ Cox, S Dwyer… - Journal of Allergy and …, 2017 - Elsevier
Background Patients with asthma and healthy controls differ in bacterial colonization of the
respiratory tract. The upper airways have been shown to reflect colonization of the lower …

Immunity against Moraxella catarrhalis requires guanylate‐binding proteins and caspase‐11‐NLRP3 inflammasomes

D Enosi Tuipulotu, S Feng, A Pandey, A Zhao… - The EMBO …, 2023 - embopress.org
Moraxella catarrhalis is an important human respiratory pathogen and a major causative
agent of otitis media and chronic obstructive pulmonary disease. Toll‐like receptors …

Comparing the healthy nose and nasopharynx microbiota reveals continuity as well as niche-specificity

I De Boeck, S Wittouck, S Wuyts… - Frontiers in …, 2017 - frontiersin.org
To improve our understanding of upper respiratory tract (URT) diseases and the underlying
microbial pathogenesis, a better characterization of the healthy URT microbiome is crucial …

Maternal prenatal immunity, neonatal trained immunity, and early airway microbiota shape childhood asthma development

A DeVries, K McCauley, D Fadrosh, KE Fujimura… - Allergy, 2022 - Wiley Online Library
Background The path to childhood asthma is thought to initiate in utero and be further
promoted by postnatal exposures. However, the underlying mechanisms remain …

Multicomponent Moraxella catarrhalis outer membrane vesicles induce an inflammatory response and are internalized by human epithelial cells

V Schaar, SPW De Vries… - Cellular …, 2011 - Wiley Online Library
Moraxella catarrhalis is an emerging human respiratory pathogen in patients with chronic
obstructive pulmonary disease (COPD) and in children with acute otitis media. The specific …

A four-part guide to lung immunology: Invasion, inflammation, immunity, and intervention

I Gopallawa, R Dehinwal, V Bhatia, V Gujar… - Frontiers in …, 2023 - frontiersin.org
Lungs are important respiratory organs primarily involved in gas exchange. Lungs interact
directly with the environment and their primary function is affected by several inflammatory …

Differential adaptation of microbial pathogens to airways of patients with cystic fibrosis and chronic obstructive pulmonary disease

G Döring, IG Parameswaran… - FEMS microbiology …, 2011 - academic.oup.com
Cystic fibrosis (CF), the most common autosomal recessive disorder in Caucasians, and
chronic obstructive pulmonary disease (COPD), a disease of adults, are characterized by …