Abstract Tumour Necrosis Factor α (TNFα), is an inflammatory cytokine produced by
macrophages/monocytes during acute inflammation and is responsible for a diverse range …

Tumor necrosis factor (TNF) and lymphotoxin-α were isolated more than 10 years ago, on
the basis of their ability to kill tumor cells in vitro and to cause hemorrhagic necrosis of …

Bacterial pneumonia is an increasing complication of HIV infection and inversely correlates
with the CD4+ lymphocyte count. Interleukin (IL)-17 is a cytokine produced principally by …

Recent studies have focused their attention on the role of the proinflammatory cytokine
tumor necrosis factor (TNF) in the development of heart failure. First recognized as an …

Alveolar macrophages represent a first-line innate host defense mechanism for clearing
inhaled Aspergillus fumigatus from the lungs, yet contradictory data exist as to which …

Currently, the preferred host for the production of early region-1 (E1)-deleted recombinant
adenoviruses (rAdV) is cell line 293, which was generated by transformation of human …

Abstract IL-25 (IL-17E) is a unique IL-17 family ligand that promotes Th2-skewed
inflammatory responses. Intranasal administration of IL-25 into naive mice induces …

Heme oxygenase-1 (HO-1) confers protection against a variety of oxidant-induced cell and
tissue injury. In this study, we examined whether exogenous administration of HO-1 by gene …

We examined the effects of upregulation of heme oxygenase-1 (HO-1) in steatotic rat liver
models of ex vivo cold ischemia/reperfusion (I/R) injury. In the model of ischemia/isolated …

Myocardial fibrosis caused by maladaptive extracellular matrix (ECM) remodeling is
implicated in the dysfunction of the failing heart. Matrix metalloproteinases (MMPs) regulate …