The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

Individuals living with human immunodeficiency virus type 1 (HIV-1) are often plagued by
debilitating neurocognitive impairments and affective alterations; the pathophysiology …

The fronto-striatal circuitry, involving the nucleus accumbens, ventral tegmental area, and
prefrontal cortex, mediates goal-directed behavior and is targeted by both drugs of abuse …

The persistence of HIV-1 viral reservoirs in the brain, despite treatment with combination
antiretroviral therapy (cART), remains a critical roadblock for the development of a novel …

A review of the association between microbes and mental illness is performed, including the
history, relevant definitions, infectious agents associated with mental illnesses, complex …

Chemical transmission between neurosecretory cells is a central biological phenomenon.
Detecting neurotransmitter molecules released in the brain or in cell cultures is key to …

Independently, chronic cocaine use and HIV-1 viral protein exposure induce
neuroadaptations in the frontal-striatal circuit as evidenced by both clinical and preclinical …

Despite decades of advancements in HIV treatment, the persistence of viral reservoirs
necessitates lifelong therapy, complicating efforts to fully control the infection. Nucleoside …

Motivational deficits (eg, apathy) and dysregulation (eg, addiction) in HIV-1 seropositive
individuals, despite treatment with combination antiretroviral therapy, necessitates the …

Despite the advent of combination anti‐retroviral therapy (cART), nearly half of people
infected with HIV treated with cART still exhibit HIV‐associated neurocognitive disorders …