The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis

K Dheda, T Gumbo, G Maartens, KE Dooley… - The lancet Respiratory …, 2017 - thelancet.com
Global tuberculosis incidence has declined marginally over the past decade, and
tuberculosis remains out of control in several parts of the world including Africa and Asia …

Tuberculous meningitis

RJ Wilkinson, U Rohlwink, UK Misra… - Nature reviews …, 2017 - nature.com
Tuberculosis remains a global health problem, with an estimated 10.4 million cases and 1.8
million deaths resulting from the disease in 2015. The most lethal and disabling form of …

Adjunctive dexamethasone for tuberculous meningitis in HIV-positive adults

J Donovan, ND Bang, D Imran… - … England Journal of …, 2023 - Mass Medical Soc
Background Adjunctive glucocorticoids are widely used to treat human immunodeficiency
virus (HIV)–associated tuberculous meningitis despite limited data supporting their safety …

Official American thoracic society/centers for disease control and prevention/infectious diseases society of America clinical practice guidelines: treatment of drug …

P Nahid, SE Dorman, N Alipanah… - Clinical infectious …, 2016 - academic.oup.com
Abstract The American Thoracic Society, Centers for Disease Control and Prevention, and
Infectious Diseases Society of America jointly sponsored the development of this guideline …

Diagnosis and treatment of extrapulmonary tuberculosis

JY Lee - Tuberculosis and respiratory diseases, 2015 - synapse.koreamed.org
Extrapulmonary tuberculosis (EPTB) constitutes about 20% of all cases of tuberculosis (TB)
in Korea. Diagnosing EPTB remains challenging because clinical samples obtained from …

Treatment of tuberculosis

CR Horsburgh Jr, CE Barry III… - New England Journal of …, 2015 - Mass Medical Soc
Treatment of Tuberculosis | New England Journal of Medicine Skip to main content The New
England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …

An overview of new antitubercular drugs, drug candidates, and their targets

A Bahuguna, DS Rawat - Medicinal research reviews, 2020 - Wiley Online Library
The causative agent of tuberculosis (TB), Mycobacterium tuberculosis and more recently
totally drug‐resistant strains of M. tuberculosis, display unique mechanisms to survive in the …

Tuberculous meningitis: more questions, still too few answers

GE Thwaites, R van Toorn, J Schoeman - The Lancet Neurology, 2013 - thelancet.com
Tuberculous meningitis is especially common in young children and people with untreated
HIV infection, and it kills or disables roughly half of everyone affected. Childhood disease …

Intensified antituberculosis therapy in adults with tuberculous meningitis

AD Heemskerk, ND Bang, NTH Mai… - … England Journal of …, 2016 - Mass Medical Soc
Background Tuberculous meningitis is often lethal. Early antituberculosis treatment and
adjunctive treatment with glucocorticoids improve survival, but nearly one third of patients …

A dose-ranging trial to optimize the dose of rifampin in the treatment of tuberculosis

MJ Boeree, AH Diacon, R Dawson… - American journal of …, 2015 - atsjournals.org
Rationale: Rifampin at a dose of 10 mg/kg was introduced in 1971 based on
pharmacokinetic, toxicity, and cost considerations. Available data in mice and humans …