Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) is a myelopoietic growth
factor that has pleiotropic effects not only in promoting the differentiation of immature …

Rheumatoid arthritis (RA) is an autoimmune disease that generally affects the joints. In the
late stages of the disease, it can be associated with several complications. Although the …

Introduction The last decade has led to rapid developments and increased usage of
computational tools at the single-cell level. However, our knowledge remains limited in how …

Granulocyte colony-stimulating factor (G-CSF) has been widely used to mobilize bone
marrow hematopoietic stem/progenitor cells for transplantation in the treatment of …

Granulocyte-macrophage-colony stimulating factor (GM-CSF), can direct the activation,
proliferation and differentiation of myeloid-derived cells. It is also responsible for maturation …

Repurposing drugs and adjuvants is an attractive choice of present therapy that reduces the
substantial costs, chances of failure, and systemic toxicity. Mycobacterium indicus pranii was …

Inspired by Waddington's illustration of an epigenetic landscape, cell-fate transitions have
been envisioned as bifurcating dynamical systems, wherein exogenous signaling dynamics …

Hematopoietic stem cells (HSCs) are tightly regulated by specific microenvironments called
niches to produce an appropriate number of mature blood cell types. Self-renewal and …

Colony Stimulating Factor 1 Receptor (CSF1R) is a potential target for anti-epileptic drugs.
However, inhibition of CSF1R is not well tolerated by patients, thereby prompting the need …

Aproper choice of neutrophil-macrophage progenitor cell fate is essential for the generation
of adequate myeloid subpopulations during embryonic development and in adulthood. The …