Giardia duodenalis: biology and pathogenesis

RD Adam - Clinical microbiology reviews, 2021 - Am Soc Microbiol
Giardia duodenalis captured the attention of Leeuwenhoek in 1681 while he was examining
his own diarrheal stool, but, ironically, it did not really gain attention as a human pathogen …

Host specificity in the Giardia duodenalis species complex

SM Cacciò, M Lalle, SG Svärd - Infection, Genetics and Evolution, 2018 - Elsevier
Giardia duodenalis is a unicellular flagellated parasite that infects the gastrointestinal tract of
a wide range of mammalian species, including humans. Investigations of protein and DNA …

[HTML][HTML] Giardia duodenalis induces pathogenic dysbiosis of human intestinal microbiota biofilms

JK Beatty, SV Akierman, JP Motta, S Muise… - International journal for …, 2017 - Elsevier
Giardia duodenalis is a prevalent cause of acute diarrheal disease worldwide. However,
recent outbreaks in Italy and Norway have revealed a link between giardiasis and the …

Giardia spp. and the Gut Microbiota: Dangerous Liaisons

E Fekete, T Allain, A Siddiq, O Sosnowski… - Frontiers in …, 2021 - frontiersin.org
Alteration of the intestinal microbiome by enteropathogens is commonly associated with
gastrointestinal diseases and disorders and has far-reaching consequences for overall …

Characterization of the Giardia intestinalis secretome during interaction with human intestinal epithelial cells: The impact on host cells

SY Ma'ayeh, J Liu, D Peirasmaki… - PLoS neglected …, 2017 - journals.plos.org
Background Giardia intestinalis is a non-invasive protozoan parasite that causes giardiasis
in humans, the most common form of parasite-induced diarrhea. Disease mechanisms are …

Pathogenesis and post-infectious complications in giardiasis

T Allain, AG Buret - Advances in parasitology, 2020 - Elsevier
Giardia is an important cause of diarrhoea, and results in post-infectious and extra-intestinal
complications. This chapter presents a state-of-the art of our understanding of how this …

Secreted Giardia intestinalis cysteine proteases disrupt intestinal epithelial cell junctional complexes and degrade chemokines

J Liu, S Ma'ayeh, D Peirasmaki… - Virulence, 2018 - Taylor & Francis
Giardiasis is a common diarrheal disease caused by the protozoan parasite Giardia
intestinalis. Cysteine proteases (CPs) are acknowledged as virulence factors in Giardia but …

Extracellular Cysteine Proteases of Key Intestinal Protozoan Pathogens—Factors Linked to Virulence and Pathogenicity

R Argüello-García, JC Carrero… - International Journal of …, 2023 - mdpi.com
Intestinal diseases caused by protistan parasites of the genera Giardia (giardiasis),
Entamoeba (amoebiasis), Cryptosporidium (cryptosporidiosis) and Blastocystis …

Interactions of Giardia sp. with the intestinal barrier: Epithelium, mucus, and microbiota

T Allain, CB Amat, JP Motta, A Manko, AG Buret - Tissue Barriers, 2017 - Taylor & Francis
Understanding how intestinal enteropathogens cause acute and chronic alterations has
direct animal and human health perspectives. Significant advances have been made on this …

The possible role of bacteria, viruses, and parasites in initiation and exacerbation of irritable bowel syndrome

A Shariati, F Fallah, A Pormohammad… - Journal of cellular …, 2019 - Wiley Online Library
Irritable bowel syndrome (IBS) is a prolonged and disabling functional gastrointestinal
disorder with the incidence rate of 18% in the world. IBS could seriously affect lifetime of …