In 2017–2019, the March of Dimes convened a workgroup with biomedical, clinical, and
epidemiologic expertise to review knowledge of the causes of the persistent Black-White …

Preterm birth contributes significantly to neonatal mortality and morbidity. Despite its global
significance, there has only been limited progress in preventing preterm birth. Spontaneous …

Preterm birth (PTB) is the leading cause of neonatal morbidity and mortality. The vaginal
microbiome has been associated with PTB, yet the mechanisms underlying this association …

Abstract In1998, the Boston Birth Cohort (BBC) was initiated at Boston Medical Center
(BMC) in response to persistently high rates of preterm birth (PTB, defined as birth before 37 …

Innovative analytical frameworks are required to capture the complex gene-environment
interactions. We investigate the insufficiency of commonly used models for disease genome …

Background Maternal smoking affects more than half a million pregnancies each year in the
US and is known to result in fetal growth restriction as measured by lower birthweight and its …

Racial and ethnic disparities in adverse birth outcomes have persistently been wide and
may be explained by individual and area-level factors. Our primary objective was to …

Background DNA methylation (DNAm) in cord blood has been associated with various
prenatal factors and birth outcomes. This study sought to fill an important knowledge gap …

Preterm birth is associated with short‐and long‐term impairments affecting physical,
cognitive, and neuropsychiatric health. These sequelae, together with a rising preterm birth …

Preterm birth affects~ 10% of pregnancies in the US. Despite familial associations,
identifying at-risk genetic loci has been challenging. We built deep learning and graphical …