Advances in development and application of influenza vaccines

J Chen, J Wang, J Zhang, H Ly - Frontiers in immunology, 2021 - frontiersin.org
Influenza A virus is one of the most important zoonotic pathogens that can cause severe
symptoms and has the potential to cause high number of deaths and great economic loss …

Genetic and biological properties of H7N9 avian influenza viruses detected after application of the H7N9 poultry vaccine in China

X Yin, G Deng, X Zeng, P Cui, Y Hou, Y Liu… - PLoS …, 2021 - journals.plos.org
The H7N9 avian influenza virus (AIV) that emerged in China have caused five waves of
human infection. Further human cases have been successfully prevented since September …

Insights from avian influenza surveillance of chickens and ducks before and after exposure to live poultry markets

M Li, X Yin, L Guan, X Zhang… - Science China …, 2019 - pubmed.ncbi.nlm.nih.gov
Insights from avian influenza surveillance of chickens and ducks before and after exposure
to live poultry markets Insights from avian influenza surveillance of chickens and ducks …

H3N2 avian influenza viruses detected in live poultry markets in China bind to human-type receptors and transmit in guinea pigs and ferrets

L Guan, J Shi, X Kong, S Ma, Y Zhang… - Emerging Microbes & …, 2019 - Taylor & Francis
The H3N2 influenza viruses became widespread in humans during the 1968 H3N2
pandemic and have been a major cause of influenza epidemics ever since. Different …

Divergent reassortment and transmission dynamics of highly pathogenic avian influenza a (H5N8) virus in birds of China during 2021

H Ye, J Zhang, Y Sang, N Shan, W Qiu… - Frontiers in …, 2022 - frontiersin.org
Highly pathogenic influenza A (H5N8) viruses had caused several outbreaks among wild
bird and poultry populations across the globe, and strikingly, caused human infection …

Glycosylation and an amino acid insertion in the head of hemagglutinin independently affect the antigenic properties of H5N1 avian influenza viruses

C Gu, X Zeng, Y Song, Y Li, L Liu, Y Kawaoka… - Science China Life …, 2019 - Springer
Antigenic drift forces us to frequently update influenza vaccines; however, the genetic basis
for antigenic variation remains largely unknown. In this study, we used clade 7.2 H5 viruses …

Structural basis of different neutralization capabilities of monoclonal antibodies against H7N9 virus

B Zhao, Z Sun, S Wang, Z Shi, Y Jiang, X Wang… - Journal of …, 2024 - journals.asm.org
Neutralizing antibodies (nAbs) are important for the treatment of emerging viral diseases
and for effective vaccine development. In this study, we generated and evaluated three nAbs …

The viral distribution and pathological characteristics of BALB/c mice infected with highly pathogenic Influenza H7N9 virus

XX Wu, SJ Tang, SH Yao, YQ Zhou, LL Xiao, LF Cheng… - Virology Journal, 2021 - Springer
Abstract Background The highly pathogenic Influenza H7N9 virus is believed to cause
multiple organ infections. However, there have been few systematic animal experiments …

Spatiotemporal associations and molecular evolution of highly pathogenic avian influenza A H7N9 virus in China from 2017 to 2021

D He, M Gu, X Wang, X Wang, G Li, Y Yan, J Gu… - Viruses, 2021 - mdpi.com
Highly pathogenic (HP) H7N9 avian influenza virus (AIV) emerged in China in 2016. HP
H7N9 AIV caused at least 33 human infections and has been circulating in poultry farms …

Progress and current status of influenza researches in China

T Shi, X Feng, Z Jie - Journal of Translational Internal Medicine, 2019 - degruyter.com
Influenza pandemics with different extent occur every year in the world. It can cause high
morbidity and mortality, arouse fear panic in public, and attract extensive attention …