The roles of the hippocampus and prefrontal cortex (PFC) in memory processing—
individually or in concert—are a major topic of interest in memory research. These brain …

Kraepelin, in his early descriptions of schizophrenia (SZ), characterized the illness as having
“an orchestra without a conductor.” Kraepelin further speculated that this “conductor” was …

Activity-dependent synaptic plasticity is a ubiquitous property of the nervous system that
allows neurons to communicate and change their connections as a function of past …

A core component of cognitive control–the ability to regulate thoughts and actions in
accordance with internally represented behavioral goals–might be its intrinsic variability. In …

Classic cognitive theory conceptualizes executive functions as involving multiple specific
domains, including initiation, inhibition, working memory, flexibility, planning, and vigilance …

Cognitive aging is a flourishing area of research. A significant amount of new data, a number
of new theoretical notions, and many new research issues have been generated in the past …

The prefrontal cortex has long been thought to subserve both working memory (the holding
of information online for processing) and executive functions (deciding how to manipulate …

Virtually all working memory (WM) theorists agree that control processes are a critical
component of WM function. Some set of internal mechanisms must be responsible for (1) …

Although schizophrenia is an illness that has been historically characterized by the
presence of positive symptomatology, decades of research highlight the importance of …

Cognitive deficits represent a significant characteristic of schizophrenia. However, a majority
of the clinical studies have been conducted in antipsychotic drug treated patients. Thus, it …