Unique roles of gold nanoparticles in drug delivery, targeting and imaging applications

FY Kong, JW Zhang, RF Li, ZX Wang, WJ Wang… - Molecules, 2017 - mdpi.com
Nanotechnology has become more and more potentially used in diagnosis or treatment of
diseases. Advances in nanotechnology have led to new and improved nanomaterials in …

Nanoformulations to enhance the bioavailability and physiological functions of polyphenols

B Yang, Y Dong, F Wang, Y Zhang - Molecules, 2020 - mdpi.com
Polyphenols are micronutrients that are widely present in human daily diets. Numerous
studies have demonstrated their potential as antioxidants and anti-inflammatory agents, and …

Probing cellular molecules with polyA-based engineered aptamer nanobeacon

L Chen, J Chao, X Qu, H Zhang, D Zhu… - … applied materials & …, 2017 - ACS Publications
Adenosine triphosphate (ATP) is a central metabolite that is of critical importance in many
cellular processes. The development of sensitive and selective methods for the detection of …

Gold nanoclusters as prospective carriers and detectors of pramipexole

NT Si, NTA Nhung, TQ Bui, MT Nguyen, PV Nhat - RSC advances, 2021 - pubs.rsc.org
Pramipexole (PPX) is known in the treatment of Parkinson's disease and restless legs
syndrome. We carried out a theoretical investigation on pramipexole–Au cluster interactions …

Binding mechanism and surface-enhanced Raman scattering of the antimicrobial sulfathiazole on gold nanoparticles

TN Kha, NT Si, VM Tran, KQ Vo, MT Nguyen… - ACS …, 2023 - ACS Publications
A combined study using the surface-enhanced Raman scattering (SERS) technique and
quantum chemical calculations was carried out to elucidate the adsorption behavior of …

Protein scaffolded DNA tetrads enable efficient delivery and ultrasensitive imaging of miRNA through crosslinking hybridization chain reaction

DJ Huang, ZM Huang, HY Xiao, ZK Wu, LJ Tang… - Chemical …, 2018 - pubs.rsc.org
Efficient intracellular delivery of nucleic acids to achieve sensitive detection and gene
regulation is essential for chemistry and biology. Here we developed a novel protein …

A DNA tetrahedral structure-mediated ultrasensitive fluorescent microarray platform for nucleic acid test

H Zhang, X Liu, C Zhang, Y Xu, J Su, X Lu, J Shi… - Sensors and Actuators B …, 2020 - Elsevier
Microarrays are key platforms for biomolecule detection owing to their parallelizability and
amenability for high-throughput. However, conventional fluorescent microarrays still suffer …

Gold nanoparticle based fluorescent oligonucleotide probes for imaging and therapy in living systems

Y Yang, S Zhong, K Wang, J Huang - Analyst, 2019 - pubs.rsc.org
Gold nanoparticles (AuNPs) with unique physical and chemical properties have become an
integral part of research in nanoscience. In particular, the development of AuNP-based …

In situ-prepared homogeneous supramolecular organic framework drug delivery systems (sof-DDSs): Overcoming cancer multidrug resistance and controlled release

J Tian, C Yao, WL Yang, L Zhang, DW Zhang… - Chinese Chemical …, 2017 - Elsevier
Water-soluble three-dimensional porous supramolecular organic frameworks (SOFs) have
been demonstrated as a new generation of homogeneous polycationic platforms for anti …

Loading-free supramolecular organic framework drug delivery systems (sof-DDSs) for doxorubicin: normal plasm and multidrug resistant cancer cell-adaptive delivery …

C Yao, J Tian, H Wang, DW Zhang, Y Liu… - Chinese Chemical …, 2017 - Elsevier
Four water-soluble porous supramolecular organic framework drug delivery systems (sof-
DDSs) have been used to adsorb doxorubicin (DOX) in water at physiological pH of 7.4 …