Multidrug-resistant tuberculosis

SK Sharma, A Mohan - Indian Journal of Medical Research, 2004 - repository.ias.ac.in
Multidrug-resistant tuberculosis (MDR-TB) caused by Mycobacterium tuberculosis resistant
to both isoniazid and rifampicin with or without resistance to other drugs is among the most …

Fluoroquinolones for the treatment of pulmonary tuberculosis

S Moadebi, CK Harder, MJ Fitzgerald, KR Elwood… - Drugs, 2007 - Springer
Tuberculosis (TB) continues to be a significant problem globally. Treatment includes a
multiple drug regimen with isoniazid, rifampicin (rifampin), pyrazinamide and ethambutol …

Current status of some antituberculosis drugs and the development of new antituberculous agents with special reference to their in vitro and in vivo antimicrobial …

H Tomioka - Current pharmaceutical design, 2006 - ingentaconnect.com
Tuberculosis (TB) is a growing international health concern, since it is the leading infectious
cause of death in the world today. In particular, the increasing prevalence of multidrug …

Management of multidrug‐resistant tuberculosis: update 2007

WW Yew, CC Leung - Respirology, 2008 - Wiley Online Library
Multidrug‐resistant tuberculosis (MDR‐TB) with bacillary resistance to at least isoniazid and
rifampicin in vitro is a worldwide phenomenon. Hot spots of the disease are found scattered …

Efficacy and safety of kanamycin, ethionamide, PAS and cycloserine in multidrug-resistant pulmonary tuberculosis patients.

R Prasad, SK Verma, S Sahai, S Kumar… - The Indian journal of …, 2006 - europepmc.org
Background We carried out this study to determine the efficacy and safety of a regimen
containing kanamycin, ethionamide, isoniazid, para-aminosalicylic acid (PAS) and …

Gatifloxacin and ethionamide as the foundation for therapy of tuberculosis

MH Cynamon, M Sklaney - Antimicrobial agents and …, 2003 - Am Soc Microbiol
The use of gatifloxacin (GAT) in combination with ethionamide (ETA) with or without
pyrazinamide (PZA) for a 12-week treatment period followed by an 8-week observation …

Current status and future development of antitubercular chemotherapy

GS Besra, L Kremer - Expert Opinion on Investigational Drugs, 2002 - Taylor & Francis
Tuberculosis (TB), which kills more people than any other infectious disease, was declared
a global emergency by the World Health Organization in 1993. The emergence of new …

Fluoroquinolones, the cornerstone of treatment of drug-resistant tuberculosis: a pharmacokinetic and pharmacodynamic approach

A D. Pranger, J WC Alffenaar… - Current pharmaceutical …, 2011 - benthamdirect.com
Fluoroquinolones (FQs) are important drugs to treat drug-resistant tuberculosis. In this
review we integrated pharmacokinetic properties (PK) and microbiological susceptibility …

New regimens for reducing the duration of treatment of drug‐susceptible pulmonary tuberculosis

MB Conde, JR Lapa e Silva - Drug development research, 2011 - Wiley Online Library
Tuberculosis (TB) remains an important health problem worldwide. The structure necessary
for delivering TB treatment and implementing the directly observed treatment accounts for …

Surveillance of Mycobacterium tuberculosis susceptibility to second-line drugs in Hong Kong, 1995–2002, after the implementation of DOTS-plus

KM Kam, CW Yip - … Journal of Tuberculosis and Lung Disease, 2004 - ingentaconnect.com
OBJECTIVE: To determine the trend in changes in susceptibility of Mycobacterium
tuberculosis strains, including to second-line drugs, from patients with a history of previous …