Leishmaniasis vaccine: where are we today?
L Kedzierski - Journal of global infectious diseases, 2010 - journals.lww.com
Leishmaniasis is a disease that ranges in severity from skin lesions to serious disfigurement
and fatal systemic infection. WHO has classified the disease as emerging and uncontrolled …
and fatal systemic infection. WHO has classified the disease as emerging and uncontrolled …
Vaccine candidates for leishmaniasis: a review
R Nagill, S Kaur - International immunopharmacology, 2011 - Elsevier
Leishmaniasis is a diverse group of clinical syndromes caused by protozoan parasites of the
genus Leishmania. The clinical manifestation of the disease varies from self-limiting …
genus Leishmania. The clinical manifestation of the disease varies from self-limiting …
A second generation leishmanization vaccine with a markerless attenuated Leishmania major strain using CRISPR gene editing
WW Zhang, S Karmakar, S Gannavaram, R Dey… - Nature …, 2020 - nature.com
Leishmaniasis is a neglected tropical disease caused by Leishmania protozoa transmitted
by infected sand flies. Vaccination through leishmanization with live Leishmania major has …
by infected sand flies. Vaccination through leishmanization with live Leishmania major has …
Zooming in on common immune evasion mechanisms of pathogens in phagolysosomes: potential broad-spectrum therapeutic targets against infectious diseases
The intracellular viral, bacterial, or parasitic pathogens evade the host immune challenges to
propagate and cause fatal diseases. The microbes overpower host immunity at various …
propagate and cause fatal diseases. The microbes overpower host immunity at various …
Leishmaniasis: current treatment and prospects for new drugs and vaccines
L Kedzierski, A Sakthianandeswaren… - Current medicinal …, 2009 - ingentaconnect.com
Leishmaniasis is a disease that ranges in severity from skin lesions to serious disfigurement
and fatal systemic infection. WHO estimates that the disease results in 2 million new cases a …
and fatal systemic infection. WHO estimates that the disease results in 2 million new cases a …
Intracellular replication-deficient Leishmania donovani induces long lasting protective immunity against visceral leishmaniasis
A Selvapandiyan, R Dey, S Nylen… - The Journal of …, 2009 - journals.aai.org
No vaccine is currently available for visceral leishmaniasis (VL) caused by Leishmania
donovani. This study addresses whether a live attenuated centrin gene-deleted L. donovani …
donovani. This study addresses whether a live attenuated centrin gene-deleted L. donovani …
Host–pathogen interaction in leishmaniasis: immune response and vaccination strategies
Leishmaniasis is a zoonotic and vector-borne infectious disease that is caused by the genus
Leishmania belonging to the trypanosomatid family. The protozoan parasite has a digenetic …
Leishmania belonging to the trypanosomatid family. The protozoan parasite has a digenetic …
Preclinical validation of a live attenuated dermotropic Leishmania vaccine against vector transmitted fatal visceral leishmaniasis
S Karmakar, N Ismail, F Oliveira, J Oristian… - Communications …, 2021 - nature.com
Visceral Leishmaniasis (VL), a potentially fatal disease is caused by Leishmania donovani
parasites with no vaccine available. Here we produced a dermotropic live attenuated centrin …
parasites with no vaccine available. Here we produced a dermotropic live attenuated centrin …
Expression profiling by whole-genome interspecies microarray hybridization reveals differential gene expression in procyclic promastigotes, lesion-derived …
We examined the Leishmania mexicana transcriptome to identify differentially regulated
mRNAs using high-density whole-genome oligonucleotide microarrays designed from the …
mRNAs using high-density whole-genome oligonucleotide microarrays designed from the …
Leishmaniasis and various immunotherapeutic approaches
Leishmaniasis is a vector-borne infectious disease caused by multiple Leishmania (L.)
species with diverse clinical manifestations. There is currently no vaccine against any form …
species with diverse clinical manifestations. There is currently no vaccine against any form …