Motivation. The knowledge of the subcellular localization of a protein is fundamental for
elucidating its function. It is difficult to determine the subcellular location for eukaryotic cells …

It has long been understood that specific features of a protein and its corresponding import
apparatus dictate the behavior of mitochondrial proteins in their intracellular targeting …

Background The human herpes simplex virus (HSV) h ost c ell f actor HCF-1 is a
transcriptional coregulator that associates with both histone methyl-and acetyltransferases …

The human cellular factor (HCF) is a multidomain protein that is implicated in processes of
cell cycle progression, and it is recruited into a multicomponent assembly that triggers the …

Asymmetric cell division is an essential process to generate cell diversity during
development. In C. elegans, many asymmetric cell divisions are regulated by Wnt signalling …

Aging is a complex process influenced by the environment and genotype. Numerous
conserved genetic pathways and factors have been identified as key mediators of lifespan …