Deaths from opioid use are increasing in the US, with a growing proportion due to synthetic
opioids. Until 2013, sporadic outbreaks of fentanyl and fentanyl analogs contaminating the …

A number of N-alkyl indole or indazole-3-carbonyl analogs, with modified chemical
structures, are distributed throughout the world as synthetic cannabinoids. Like synthetic …

Novel psychoactive substances include synthetic cannabinoids, cathinone derivatives,
psychedelic phenethylamines, novel stimulants, synthetic opioids, tryptamine derivatives …

Synthetic cannabinoid (SC) designer drugs based on indole and indazole scaffolds and
featuring l-valinamide or l-tert-leucinamide side chains are encountered with increasing …

Synthetic cannabinoid (SC) designer drugs featuring bioisosteric fluorine substitution are
identified by forensic chemists and toxicologists with increasing frequency. Although …

The abuse of novel psychoactive substances (NPS) has been increasing dramatically
worldwide since late 2000s. By the end of 2015, more than 560 NPS had been reported to …

Introduction: The emergence of novel psychoactive substances has changed the
epidemiology of drugs used recreationally throughout Europe and have posed significant …

In recent years, many synthetic cannabinoid (CB) receptor agonists have appeared on the
market as constituents of herbal incense mixtures known as “spice”. Contrary to the declared …

Synthetic cannabinoid receptor agonists (SCRAs) have proliferated as new psychoactive
substances (NPS) over the past decade. Relative to other classes of NPS, SCRAs are …

Abstract From November 2013 to May 2014, 19 newly distributed designer drugs were
identified in 104 products in our ongoing survey of illegal products in Japan. The identified …