In normal prostate, neuroendocrine (NE) cells are rare and interspersed among the
epithelium. These cells are believed to provide trophic signals to epithelial cell populations …

Prostate cancer (PCa) is the most diagnosed malignancy in the men worldwide. Cancer
stem cells (CSCs) are the sub-population of cells present in the tumor which possess unique …

Expression of class III β-tubulin (βIII-tubulin) correlates with tumor progression and
resistance to taxane-based therapies for several human malignancies, but its use as a …

Prostate cancer co-opts a unique set of cellular pathways in its initiation and progression.
The heterogeneity of prostate cancers is evident at earlier stages, and has led to rigorous …

Activation of Hedgehog (Hh) signaling is implicated in the development and progression of
several tumor types, including prostate cancer, which is still the most common non-skin …

Simple Summary Although epithelial-to-mesenchymal transition (EMT) is a well-known
cellular process involved during normal embryogenesis and wound healing, it also has a …

The HEDGEHOG-GLI (HH-GLI) signalling is a key pathway critical in embryonic
development, stem cell biology and tissue homeostasis. In recent years, aberrant activation …

Purpose: Recent evidence indicates that small noncoding RNA molecules, known as
microRNAs (miRNAs), are involved in cancer initiation and progression. We hypothesized …

Background: Class III β-tubulin (βIII-tubulin) is expressed in tissues of neuronal lineage and
also in several human malignancies, including non-small-cell lung carcinoma, breast and …

Aberrant activation of the hedgehog (Hh) signaling pathway has been implicated in the
epithelial-to-mesenchymal transition (EMT) and cancer stem-like cell (CSC) maintenance; …