Pathogenicity Factors of Genomic Islands in Intestinal and Extraintestinal Escherichia coli

M Desvaux, G Dalmasso, R Beyrouthy… - Frontiers in …, 2020 - frontiersin.org
Escherichia coli is a versatile bacterial species that includes both harmless commensal
strains and pathogenic strains found in the gastrointestinal tract in humans and warm …

Molecular Pathogenesis of Shigella spp.: Controlling Host Cell Signaling, Invasion, and Death by Type III Secretion

GN Schroeder, H Hilbi - Clinical microbiology reviews, 2008 - Am Soc Microbiol
Shigella spp. are gram-negative pathogenic bacteria that evolved from harmless
enterobacterial relatives and may cause devastating diarrhea upon ingestion. Research …

Multiple independent origins of Shigella clones of Escherichia coli and convergent evolution of many of their characteristics

GM Pupo, R Lan, PR Reeves - Proceedings of the National …, 2000 - National Acad Sciences
The evolutionary relationships of 46 Shigella strains representing each of the serotypes
belonging to the four traditional Shigella species (subgroups), Dysenteriae, Flexneri, Boydii …

Biological foundations of successful bacteriophage therapy

C Venturini, A Petrovic Fabijan… - EMBO Molecular …, 2022 - embopress.org
Bacteriophages (phages) are selective viral predators of bacteria. Abundant and ubiquitous
in nature, phages can be used to treat bacterial infections (phage therapy), including …

Structure and genetics of Shigella O antigens

B Liu, YA Knirel, L Feng, AV Perepelov… - FEMS microbiology …, 2008 - academic.oup.com
This review covers the O antigens of the 46 serotypes of Shigella, but those of most Shigella
flexneri are variants of one basic structure, leaving 34 Shigella distinct O antigens to review …

Serotype-converting bacteriophages and O-antigen modification in Shigella flexneri

GE Allison, NK Verma - Trends in microbiology, 2000 - cell.com
O-antigen modification (serotype conversion) in Shigella flexneri, which is an important
virulence determinant, is conferred by temperate bacteriophages. Several serotype …

Optimization of Virulence Functions Through Glucosylation of Shigella LPS

NP West, P Sansonetti, J Mounier, RM Exley, C Parsot… - Science, 2005 - science.org
Shigella, the leading cause of bacillary dysentery, uses a type III secretion system (TTSS) to
inject proteins into human cells, leading to bacterial invasion and a vigorous inflammatory …

The genomic signatures of Shigella evolution, adaptation and geographical spread

HC The, DP Thanh, KE Holt, NR Thomson… - Nature Reviews …, 2016 - nature.com
Shigella spp. are some of the key pathogens responsible for the global burden of diarrhoeal
disease. These facultative intracellular bacteria belong to the family Enterobacteriaceae …

Progress in understanding the assembly process of bacterial O-antigen

S Kalynych, R Morona, M Cygler - FEMS microbiology reviews, 2014 - academic.oup.com
The discovery that the surfaces of Gram-negative bacteria often carry unique polysaccharide
signatures pre-dates most seminal discoveries of molecular biology and biochemistry of the …

Control of directionality in integrase-mediated recombination: examination of recombination directionality factors (RDFs) including Xis and Cox proteins

JA Lewis, GF Hatfull - Nucleic acids research, 2001 - academic.oup.com
Similarity between the DNA substrates and products of integrase-mediated site-specific
recombination reactions results in a single recombinase enzyme being able to catalyze both …