Utilization of Host-Derived Glycans by Intestinal Lactobacillus and Bifidobacterium Species

M Zúñiga, V Monedero, MJ Yebra - Frontiers in microbiology, 2018 - frontiersin.org
Members of the genus Lactobacillus are commonly found at the gastrointestinal tract and
other mucosal surfaces of humans. This genus includes various species with a great number …

Human milk oligosaccharides as bioactive compounds in infant formula: recent advances and trends in synthetic methods

E Pérez-Escalante, S Alatorre-Santamaría… - Critical Reviews in …, 2022 - Taylor & Francis
Human milk oligosaccharides (HMO) have attracted great interest in recent years due to
their role in boosting infants and adults health. According to several in vitro, in vivo and …

Core fucosylation of maternal milk N-glycan evokes B cell activation by selectively promoting the l-fucose metabolism of gut Bifidobacterium spp. and Lactobacillus …

M Li, Y Bai, J Zhou, W Huang, J Yan, J Tao, Q Fan… - MBio, 2019 - Am Soc Microbiol
The maternal milk glycobiome is crucial for shaping the gut microbiota of infants. Although
high core fucosylation catalyzed by fucosyltransferase 8 (Fut8) is a general feature of human …

Complex oligosaccharide utilization pathways in Lactobacillus

M Zúñiga, MJ Yebra, V Monedero - Current issues in molecular biology, 2021 - mdpi.com
Lactobacillus is the bacterial genus that contains the highest number of characterized
probiotics. Lactobacilli in general can utilize a great variety of carbohydrates. This …

Unraveling the role of the secretor antigen in human rotavirus attachment to histo-blood group antigens

R Gozalbo-Rovira, JR Ciges-Tomas… - PLoS …, 2019 - journals.plos.org
Rotavirus is the leading agent causing acute gastroenteritis in young children, with the P [8]
genotype accounting for more than 80% of infections in humans. The molecular bases for …

Infant-gut associated Bifidobacterium dentium strains utilize the galactose moiety and release lacto-N-triose from the human milk oligosaccharides lacto-N-tetraose …

EM Moya-Gonzálvez, A Rubio-del-Campo… - Scientific reports, 2021 - nature.com
Much evidence suggests a role for human milk oligosaccharides (HMOs) in establishing the
infant microbiota in the large intestine, but the response of particular bacteria to individual …

[HTML][HTML] Biochemical characterization of a novel β-galactosidase from Lacticaseibacillus zeae and its application in synthesis of lacto-N-tetraose

T Li, J Li, Q Yan, S Yang, Z Jiang - Journal of Dairy Science, 2023 - Elsevier
ABSTRACT Lacto-N-tetraose (LNT) is one of the most important components of human milk
oligosaccharides, which has various beneficial health effects. β-Galactosidase is an …

[HTML][HTML] NMR chemical shift prediction and structural elucidation of linker-containing oligo-and polysaccharides using the computer program CASPER

KM Dorst, G Widmalm - Carbohydrate research, 2023 - Elsevier
Carbohydrate structures containing alkyl groups as aglycones are useful for investigating
enzyme activity and glycan-protein interactions. Moreover, linker-containing …

Reprogramming the Metabolic Network in Kluyveromyces lactis with a Transcriptional Switch for De Novo Lacto-N-biose Synthesis

F Li, W Ma, L Liu, K Niu, D Liu, W Yin… - Journal of Agricultural …, 2023 - ACS Publications
Lacto-N-biose (LNB) is a member of the human milk oligosaccharide (HMO) family and is
synthesized via an enzymatic reaction in vitro with N-acetylglucosamine (GlcNAc) and …

Enzymatic Hydrolysis of Human Milk Oligosaccharides. The Molecular Mechanism of Bifidobacterium Bifidum Lacto-N-biosidase

I Cuxart, J Coines, O Esquivias, M Faijes, A Planas… - ACS …, 2022 - ACS Publications
Bifidobacterium bifidum lacto-N-biosidase (LnbB) is a critical enzyme for the degradation of
human milk oligosaccharides in the gut microbiota of breast-fed infants. Guided by recent …