The integrated brain network that controls respiration

F Krohn, M Novello, RS van der Giessen, CI De Zeeuw… - Elife, 2023 - elifesciences.org
Respiration is a brain function on which our lives essentially depend. Control of respiration
ensures that the frequency and depth of breathing adapt continuously to metabolic needs. In …

Low-and high-level coordination of orofacial motor actions

D Kleinfeld, M Deschênes, MN Economo… - Current Opinion in …, 2023 - Elsevier
Orofacial motor actions are movements that, in rodents, involve whisking of the vibrissa,
deflection of the nose, licking and lapping with the tongue, and consumption through …

Latent neural population dynamics underlying breathing, opioid-induced respiratory depression and gasping

NE Bush, JM Ramirez - Nature Neuroscience, 2024 - nature.com
Breathing is vital and must be concurrently robust and flexible. This rhythmic behavior is
generated and maintained within a rostrocaudally aligned set of medullary nuclei called the …

Neural mechanisms for the localization of unexpected external motion

S Chinta, SR Pluta - Nature Communications, 2023 - nature.com
To localize objects during active sensing, animals must differentiate stimuli caused by
volitional movement from real-world object motion. To determine a neural basis for this …

[HTML][HTML] Role of NaV1. 6-mediated persistent sodium current and bursting-pacemaker properties in breathing rhythm generation

CA da Silva, CJ Grover, MCD Picardo, CA Del Negro - Cell reports, 2023 - cell.com
Inspiration is the inexorable active phase of breathing. The brainstem pre-Bötzinger complex
(preBötC) gives rise to inspiratory neural rhythm, but its underlying cellular and ionic bases …

Dynamic assemblies of parvalbumin interneurons in brain oscillations

YC Huang, HC Chen, YT Lin, ST Lin, Q Zheng… - Neuron, 2024 - cell.com
Brain oscillations are crucial for perception, memory, and behavior. Parvalbumin-expressing
(PV) interneurons are critical for these oscillations, but their population dynamics remain …

Brainstem control of vocalization and its coordination with respiration

J Park, S Choi, J Takatoh, S Zhao, A Harrahill, BX Han… - Science, 2024 - science.org
Phonation critically depends on precise controls of laryngeal muscles in coordination with
ongoing respiration. However, the neural mechanisms governing these processes remain …

Theory of hierarchically organized neuronal oscillator dynamics that mediate rodent rhythmic whisking

D Golomb, JD Moore, A Fassihi, J Takatoh, V Prevosto… - Neuron, 2022 - cell.com
Rodents explore their environment through coordinated orofacial motor actions, including
whisking. Whisking can free-run via an oscillator of inhibitory neurons in the medulla and …

A change in behavioral state switches the pattern of motor output that underlies rhythmic head and orofacial movements

SM Liao, D Kleinfeld - Current Biology, 2023 - cell.com
The breathing rhythm serves as a reference that paces orofacial motor actions and
orchestrates active sensing. Past work has reported that pacing occurs solely at a fixed …

Interchangeable role of motor cortex and reafference for the stable execution of an orofacial action

MA Elbaz, M Demers, D Kleinfeld, C Ethier… - Journal of …, 2023 - Soc Neuroscience
Animals interact with their environment through mechanically active, mobile sensors. The
efficient use of these sensory organs implies the ability to track their position; otherwise …