MJ Perugorria, P Olaizola, I Labiano… - Nature reviews …, 2019 - nature.com
The canonical Wnt–β-catenin pathway is a complex, evolutionarily conserved signalling mechanism that regulates fundamental physiological and pathological processes. Wnt–β …
Nonalcoholic fatty liver disease (NAFLD) is a major cause of chronic liver disease. There is uncertainty around the economic burden of NAFLD. We constructed a steady‐state …
M Levrero, J Zucman-Rossi - Journal of hepatology, 2016 - Elsevier
Hepatitis B virus (HBV) contributes to hepatocellular carcinoma (HCC) development through direct and indirect mechanisms. HBV DNA integration into the host genome occurs at early …
C Shen, X Jiang, M Li, Y Luo - Cancers, 2023 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is a global health challenge. Hepatitis virus infection (including HBV, HCV and HDV) is one of the major risk factors for HCC …
M Ringehan, JA McKeating… - … Transactions of the …, 2017 - royalsocietypublishing.org
Hepatitis B and C viruses are a global health problem causing acute and chronic infections that can lead to liver cirrhosis and hepatocellular carcinoma (HCC). These infections are the …
CM Wong, FHC Tsang, IOL Ng - Nature reviews Gastroenterology & …, 2018 - nature.com
Hepatocellular carcinoma (HCC) is a leading lethal malignancy worldwide. However, the molecular mechanisms underlying liver carcinogenesis remain poorly understood. Over the …
Z Huang, JK Zhou, Y Peng, W He, C Huang - Molecular cancer, 2020 - Springer
Hepatocellular carcinoma (HCC) is the most frequent subtype of primary liver cancer and one of the leading causes of cancer-related death worldwide. However, the molecular …
T Tu, MA Budzinska, NA Shackel, S Urban - Viruses, 2017 - mdpi.com
Chronic infection with the Hepatitis B Virus (HBV) is a major cause of liver-related morbidity and mortality. One peculiar observation in cells infected with HBV (or with closely‑related …
M Klingenberg, A Matsuda, S Diederichs, T Patel - Journal of hepatology, 2017 - Elsevier
The majority of the human genome is not translated into proteins but can be transcribed into RNA. Even though the resulting non-coding RNAs (ncRNAs) do not encode for proteins …