ASCO Guidelines provide recommendations with comprehensive review and analyses of
the relevant literature for each recommendation, following the guideline development …

Background This study compared the advantages and disadvantages of total neoadjuvant
therapy (TNT) strategies for patients with locally advanced rectal cancer, compared with the …

Aim Multiple neoadjuvant therapy strategies have been used and compared for rectal
cancer and there has been no true consensus as to the optimal neoadjuvant therapy …

Neoadjuvant short course radiotherapy (SCRT) followed by consolidation chemotherapy
(CCT) is an alternative treatment for locally advanced rectal cancer (LARC). We performed …

Background and purpose The role of preoperative short-course radiotherapy (SCRT) in
rectal cancer treatment, when compared to long-course radiochemotherapy (LCRT), is still …

Background The improved overall survival (OS) after short course preoperative radiotherapy
(SCPRT) using 5× 5 Gy reported in the early rectal cancer trials could not be replicated in …

Purpose Preoperative short-course radiotherapy (PSRT) and preoperative long-course
radiotherapy (PLRT) are standard treatment regimens for locally advanced rectal cancer …

Chemoradiotherapy (CRT) is extensively used prior to surgery for rectal cancer to provide
significantly better local control, but the radiotherapy (RT), as the other component of CRT …

Background and Objectives: Despite advances in treatment, local recurrence remains a
great concern in patients with rectal cancer. The aim of this study was to investigate the …

The management of patients with “locally advanced rectal cancer”(LARC) is evolving from
the original aim of reducing local recurrence. Current practice recognises the importance of …