Valproic acid and its derivatives are common drugs used in the treatment of epilepsy, a
result of CNS disorders. Because the molecular structure of valproic acid, as a fatty acid …

After oral administration, drug absorption from solid dosage forms depends on the release of
the drug active compounds from the dosage form, the dissolution or solubilization of the drug …

Introduction Tablet splitting is the process of dividing a tablet into portions to obtain a
prescribed dose of medication. Very few studies have investigated whether split parts of a …

ABSTRACT Objective: Lennox–Gastaut syndrome (LGS) is mainly treated with antiepileptic
drugs (AEDs) but using one AED is not sufficient to relieve all or even most patients. A …

Valproic acid and its derivatives are common drugs used in the treatment of epilepsy, a
result of CNS disorders. Because the molecular structure of valproic acid, as a fatty acid …

Valproic acid and its derivatives are common drugs used in the treatment of epilepsy, a
result of CNS disorders. Because the molecular structure of valproic acid, as a fatty acid …

En la última mitad de presente siglo se ha tratado de prolongar el efecto de un principio
activo o fármaco a través de la modulación de su liberación desde la forma farmacéutica. En …