A review of executive function deficits in autism spectrum disorder and attention-deficit/hyperactivity disorder

F Craig, F Margari, AR Legrottaglie… - Neuropsychiatric …, 2016 - Taylor & Francis
Executive dysfunction has been shown to be a promising endophenotype in
neurodevelopmental disorders such as autism spectrum disorder (ASD) and attention …

SNAP-25, a known presynaptic protein with emerging postsynaptic functions

F Antonucci, I Corradini, G Fossati… - Frontiers in synaptic …, 2016 - frontiersin.org
A hallmark of synaptic specializations is their dependence on highly organized complexes of
proteins that interact with each other. The loss or modification of key synaptic proteins …

Protein misfolding and aggregation in the brain: common pathogenetic pathways in neurodegenerative and mental disorders

A Ochneva, Y Zorkina, O Abramova, O Pavlova… - International journal of …, 2022 - mdpi.com
Mental disorders represent common brain diseases characterized by substantial
impairments of social and cognitive functions. The neurobiological causes and mechanisms …

[HTML][HTML] Synaptic genes and neurodevelopmental disorders: From molecular mechanisms to developmental strategies of behavioral testing

C Michetti, A Falace, F Benfenati, A Fassio - Neurobiology of Disease, 2022 - Elsevier
Synaptopathies are a class of neurodevelopmental disorders caused by modification in
genes coding for synaptic proteins. These proteins oversee the process of …

Prenatal exposure to valproic acid affects microglia and synaptic ultrastructure in a brain-region-specific manner in young-adult male rats: relevance to autism …

M Gąssowska-Dobrowolska, M Cieślik… - International journal of …, 2020 - mdpi.com
Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental
conditions categorized as synaptopathies. Environmental risk factors contribute to ASD …

SNARE complex in developmental psychiatry: neurotransmitter exocytosis and beyond

RB Cupertino, DB Kappel, CE Bandeira… - Journal of Neural …, 2016 - Springer
Multiple biological processes throughout development require intracellular vesicular
trafficking, where the SNARE (soluble N-ethylmaleimide-sensitive factor (NSF) attachment …

16p11. 2 CNV gene Doc2α functions in neurodevelopment and social behaviors through interaction with Secretagogin

QW Wang, J Qin, YF Chen, Y Tu, YY Xing, Y Wang… - Cell Reports, 2023 - cell.com
Copy-number variations (CNVs) of the human 16p11. 2 genetic locus are associated with
neurodevelopmental disorders, including autism spectrum disorders (ASDs) and …

[HTML][HTML] Age-related effects of X-ray irradiation on mouse hippocampus

A Casciati, K Dobos, F Antonelli, A Benedek… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Therapeutic irradiation of pediatric and adult patients can profoundly affect adult
neurogenesis, and cognitive impairment manifests as a deficit in hippocampal-dependent …

A review of the role of synaptosomal-associated protein 25 (SNAP-25) in neurological disorders

A Noor, S Zahid - International journal of neuroscience, 2017 - Taylor & Francis
Synaptosomal-associated protein 25 kDa (SNAP-25) is one of the key proteins involved in
the formation of neural soluble N-ethylmaleimide-sensitive factor attachment protein …

An altered glial phenotype in the NL3R451C mouse model of autism

SM Matta, Z Moore, FR Walker, EL Hill-Yardin… - Scientific Reports, 2020 - nature.com
Abstract Autism Spectrum Disorder (ASD; autism) is a neurodevelopmental disorder
characterised by deficits in social communication, and restricted and/or repetitive …