Cystatins are endogenous and reversible inhibitors of cysteine peptidases that are important
players in cancer progression. Besides their primary role as regulators of cysteine peptidase …

Estrogen action is mediated by various genes, including estrogen-responsive genes
(ERGs). ERGs have been used as reporter-genes and markers for gene expression. Gene …

Karanjin, an abundantly occurring furanoflavonoid in edible and non-edible legumes, exerts
diverse biological effects in vivo, and in vitro. Its potential as an anticancer agent is gaining …

Despite advances in early detection and treatment, invasion and metastasis of breast tumors
remains a major hurdle. Cystatin A (CSTA, also called stefin A), an estrogen-regulated gene …

Background Metastasis is one of the main obstacles impeding the survival of
nasopharyngeal carcinoma (NPC) patients, with the molecular mechanism underlying NPC …

Background The effect of pharmacological treatment of gastric cancer (GC) is limited, thus, it
holds significant scientific importance to thoroughly investigate the molecular mechanisms …

Pancreatic ductal adenocarcinoma (PDAC) is a disease with poor prognosis due to
diagnostic and therapeutic limitations. We previously identified cystatin A (CSTA) as a PDAC …

Purpose: anastrozole is a treatment for bosom malignant growth that is utilized related to
different treatments. Many examinations have shown that anastrozole drug expands …