Patients with COVID-19: in the dark-NETs of neutrophils
SARS-CoV-2 infection poses a major threat to the lungs and multiple other organs,
occasionally causing death. Until effective vaccines are developed to curb the pandemic, it …
occasionally causing death. Until effective vaccines are developed to curb the pandemic, it …
Risk factors of severe COVID-19: a review of host, viral and environmental factors
The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …
asymptomatic infections to severe disease and death. Understanding the risk factors of …
Accelerated biological aging in COVID-19 patients
Chronological age is a risk factor for SARS-CoV-2 infection and severe COVID-19. Previous
findings indicate that epigenetic age could be altered in viral infection. However, the …
findings indicate that epigenetic age could be altered in viral infection. However, the …
Blood DNA methylation and COVID-19 outcomes
J Balnis, A Madrid, KJ Hogan, LA Drake, HC Chieng… - Clinical …, 2021 - Springer
Background There are no prior reports that compare differentially methylated regions of DNA
in blood samples from COVID-19 patients to samples collected before the SARS-CoV-2 …
in blood samples from COVID-19 patients to samples collected before the SARS-CoV-2 …
Epigenetic and transcriptomic reprogramming in monocytes of severe COVID-19 patients reflects alterations in myeloid differentiation and the influence of …
G Godoy-Tena, A Barmada, O Morante-Palacios… - Genome Medicine, 2022 - Springer
Background COVID-19 manifests with a wide spectrum of clinical phenotypes, ranging from
asymptomatic and mild to severe and critical. Severe and critical COVID-19 patients are …
asymptomatic and mild to severe and critical. Severe and critical COVID-19 patients are …
Long COVID or post-COVID-19 condition: past, present and future research directions
C Fernández-de-Las-Peñas, AV Raveendran… - Microorganisms, 2023 - mdpi.com
The presence of symptoms after an acute SARS-CoV-2 infection (long-COVID) has become
a worldwide healthcare emergency but remains underestimated and undertreated due to a …
a worldwide healthcare emergency but remains underestimated and undertreated due to a …
The contributory role of lymphocyte subsets, pathophysiology of lymphopenia and its implication as prognostic and therapeutic opportunity in COVID-19
M Delshad, N Tavakolinia… - International …, 2021 - Elsevier
The incidence of the novel coronavirus disease (COVID-19) outbreak caused by the severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has brought daunting …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has brought daunting …
Human brain microvascular endothelial cells exposure to SARS-CoV-2 leads to inflammatory activation through NF-κB non-canonical pathway and mitochondrial …
CS Motta, S Torices, BG da Rosa, AC Marcos… - Viruses, 2023 - mdpi.com
Neurological effects of COVID-19 and long-COVID-19, as well as neuroinvasion by SARS-
CoV-2, still pose several questions and are of both clinical and scientific relevance. We …
CoV-2, still pose several questions and are of both clinical and scientific relevance. We …
Longitudinal study of DNA methylation and epigenetic clocks prior to and following test-confirmed COVID-19 and mRNA vaccination
APS Pang, AT Higgins-Chen, F Comite, I Raica… - Frontiers in …, 2022 - frontiersin.org
The host epigenetic landscape rapidly changes during SARS-CoV-2 infection, and evidence
suggest that severe COVID-19 is associated with durable scars to the epigenome …
suggest that severe COVID-19 is associated with durable scars to the epigenome …
A machine learning approach utilizing DNA methylation as an accurate classifier of COVID-19 disease severity
S Bowler, G Papoutsoglou, A Karanikas… - Scientific Reports, 2022 - nature.com
Since the onset of the COVID-19 pandemic, increasing cases with variable outcomes
continue globally because of variants and despite vaccines and therapies. There is a need …
continue globally because of variants and despite vaccines and therapies. There is a need …