Abstract RNA N6-methyladenosine (m6A) modification is one of the main forms of
posttranscriptional modification, and its dysregulation is involved in a series of pathological …

MicroRNAs (miRNAs) are believed to play important roles in mammalian spermatogenesis
mainly because spermatogenesis is more or less disrupted when genes encoding key …

Reports that mouse sperm gain small RNAs from the epididymosomes secreted by
epididymal epithelial cells and that these" foreign" small RNAs act as an epigenetic …

The intricate processes that govern the interactions between peripatetic immune cells and
distal renal injury in obesity are not fully understood. Employing transcriptomic analysis of …

As one of the post-transcriptional regulatory mechanisms, uncoupling of transcription and
translation plays an essential role in development and adulthood physiology. However, it …

The X-linked miR-465 cluster is highly expressed in the testis, sperm, newborn ovary, and
blastocysts as well as in 8-16 cell embryos. However, the physiological role of the miR-465 …

As an alternative and complementary approach to Cas9-based genome editing, Cas12a has
not been widely used in mammalian cells largely due to its strict requirement for the TTTV …

Irritable bowel syndrome (IBS) is a common chronic functional gastrointestinal disorder
defined by disturbances in bowel habits and abdominal pain, in the absence of known …

Despite rapid evolution across eutherian mammals, the X-linked MIR-506 family miRNAs
are located in a region flanked by two highly conserved protein-coding genes (SLITRK2 and …

Vertebrate branchial arches (BAs) are a developmental paradigm, undergoing coordinated
differentiation and morphogenesis to form various adult derivative tissues. MicroRNAs can …