[HTML][HTML] Individual differences in computational psychiatry: A review of current challenges

P Karvelis, MP Paulus, AO Diaconescu - Neuroscience & Biobehavioral …, 2023 - Elsevier
Bringing precision to the understanding and treatment of mental disorders requires
instruments for studying clinically relevant individual differences. One promising approach is …

Improving the reliability of cognitive task measures: A narrative review

S Zorowitz, Y Niv - Biological Psychiatry: Cognitive Neuroscience and …, 2023 - Elsevier
Cognitive tasks are capable of providing researchers with crucial insights into the
relationship between cognitive processing and psychiatric phenomena. However, many …

Reinforcement learning in patients with mood and anxiety disorders vs control individuals: A systematic review and meta-analysis

AC Pike, OJ Robinson - JAMA psychiatry, 2022 - jamanetwork.com
Importance Computational psychiatry studies have investigated how reinforcement learning
may be different in individuals with mood and anxiety disorders compared with control …

Humans primarily use model-based inference in the two-stage task

C Feher da Silva, TA Hare - Nature Human Behaviour, 2020 - nature.com
Distinct model-free and model-based learning processes are thought to drive both typical
and dysfunctional behaviours. Data from two-stage decision tasks have seemingly shown …

Advances in the computational understanding of mental illness

QJM Huys, M Browning, MP Paulus… - …, 2021 - nature.com
Computational psychiatry is a rapidly growing field attempting to translate advances in
computational neuroscience and machine learning into improved outcomes for patients …

[HTML][HTML] The promise of a model-based psychiatry: building computational models of mental ill health

TU Hauser, V Skvortsova, M De Choudhury… - The Lancet Digital …, 2022 - thelancet.com
Computational models have great potential to revolutionise psychiatry research and clinical
practice. These models are now used across multiple subfields, including computational …

[HTML][HTML] Identifying transdiagnostic mechanisms in mental health using computational factor modeling

T Wise, OJ Robinson, CM Gillan - Biological Psychiatry, 2023 - Elsevier
Most psychiatric disorders do not occur in isolation, and most psychiatric symptom
dimensions are not uniquely expressed within a single diagnostic category. Current …

Dopamine regulates decision thresholds in human reinforcement learning in males

K Chakroun, A Wiehler, B Wagner, D Mathar… - Nature …, 2023 - nature.com
Dopamine fundamentally contributes to reinforcement learning, but recent accounts also
suggest a contribution to specific action selection mechanisms and the regulation of …

Improving the reliability of computational analyses: Model-based planning and its relationship with compulsivity

VM Brown, J Chen, CM Gillan, RB Price - Biological Psychiatry: Cognitive …, 2020 - Elsevier
Background Computational models show great promise in mapping latent decision-making
processes onto dissociable neural substrates and clinical phenotypes. One prominent …

Compulsivity and impulsivity traits linked to attenuated developmental frontostriatal myelination trajectories

G Ziegler, TU Hauser, M Moutoussis, ET Bullmore… - Nature …, 2019 - nature.com
The transition from adolescence to adulthood is a period when ongoing brain development
coincides with a substantially increased risk of psychiatric disorders. The developmental …