Anticancer peptides mechanisms, simple and complex

P Norouzi, M Mirmohammadi, MHH Tehrani - Chemico-Biological …, 2022 - Elsevier
Peptide therapy has started since 1920s with the advent of insulin application, and now it
has emerged as a new approach in treatment of diseases including cancer. Using anti …

Anticancer Mechanisms and Potential Anticancer Applications of Antimicrobial Peptides and Their Nano Agents

Z Dong, X Zhang, Q Zhang… - International Journal …, 2024 - Taylor & Francis
Traditional chemotherapy is one of the main methods of cancer treatment, which is largely
limited by severe side effects and frequent development of multi-drug resistance by cancer …

Structure–activity relationships of photoswitchable diarylethene-based β-hairpin peptides as membranolytic antimicrobial and anticancer agents

O Babii, S Afonin, AY Ishchenko… - Journal of Medicinal …, 2018 - ACS Publications
Five series (28 structures) of photoswitchable β-hairpin peptides were synthesized based on
the cyclic scaffold of the natural antibiotic gramicidin S. Cell-type selectivity was compared …

[HTML][HTML] Towards in vivo photomediated delivery of anticancer peptides: Insights from pharmacokinetic and-dynamic data

IV Komarov, G Tolstanova, H Kuznietsova… - … of Photochemistry and …, 2022 - Elsevier
An in vivo study of a photoswitchable cytotoxic peptide LMB040 has been undertaken on a
chemically induced hepatocellular carcinoma model in immunocompetent rats. We analysed …

[HTML][HTML] In Vivo Behavior of the Antibacterial Peptide Cyclo[RRRWFW], Explored Using a 3-Hydroxychromone-Derived Fluorescent Amino Acid

S Afonin, S Koniev, L Préau, M Takamiya… - Frontiers in …, 2021 - frontiersin.org
Labeling biomolecules with fluorescent labels is an established tool for structural,
biochemical, and biophysical studies; however, it remains underused for small peptides. In …

Cytolytic activity of peptides derived from the Cry11Bb insecticidal toxin of B. thuringiensis subsp. medellin

S Rendon-Marin, C Quintero-Gil, VV Lemeshko… - Archives of Biochemistry …, 2021 - Elsevier
A few Bacillus thuringiensis Cry proteins, known as parasporins, have demonstrated cell
proliferation inhibition of human cancer cells in vitro after protease activation. In this work …

[PDF][PDF] Centipede venom toxins and its biomedical and pharmacological properties

N Yadav, RK Upadhyay - International Journal of Pharmacy and …, 2022 - core.ac.uk
The present review article explains venoms from various centipede species with their
biomedical and pharmacological properties. Centipede venom is a natural source of …

[PDF][PDF] Applying gata3 in differentiating urothelial carcinoma from prostatic adenocarcinoma: An immunohistochemical study

WH Abdullah, HA Kerbel… - Asian J Pharm Clin Res, 2018 - researchgate.net
Objectives: Urothelial carcinoma and prostatic adenocarcinoma are the most common
tumors of genitourinary system. Both tumors can demonstrate a broad morphology or …

[PDF][PDF] Production, characterization and bio functionalities of bioactive peptides from non-bovine species of milk: A review

KR Vadher, KM Gawai, BP Singh, P Sarkar, S Hati - researchgate.net
The exploration of bioactive peptides derived from non-bovine milk has garnered
considerable interest due to their potential health-promoting properties and functional …

[PDF][PDF] Anticancer activity of CT-p19LC, a synthetic peptide derived from the bacterial protein azurin

LF Coelho - 2017 - academia.edu
Several cationic peptides have recently been shown to display anticancer activity through a
mechanism that usually requires the disruption of cancer cell membranes. In this thesis …