[HTML][HTML] 2021 antibacterial agents in clinical and preclinical development: an overview and analysis

World Health Organization - 2022 - books.google.com
Page 1 2021 ANTIBACTERIAL AGENTS IN CLINICAL AND PRECLINICAL DEVELOPMENT:
an overview and analysis World Health Organization Page 2 A PRE Page 3 2021 …

[HTML][HTML] Sepsis—pathophysiology and therapeutic concepts

D Jarczak, S Kluge, A Nierhaus - Frontiers in medicine, 2021 - frontiersin.org
Sepsis is a life-threatening condition and a global disease burden. Today, the
heterogeneous syndrome is defined as severe organ dysfunction caused by a dysregulated …

Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021

L Evans, A Rhodes, W Alhazzani, M Antonelli… - Critical care …, 2021 - journals.lww.com
Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to
infection (1). Sepsis and septic shock are major healthcare problems, impacting millions of …

Sepsis therapies: learning from 30 years of failure of translational research to propose new leads

JM Cavaillon, M Singer, T Skirecki - EMBO molecular medicine, 2020 - embopress.org
Sepsis has been identified by the World Health Organization (WHO) as a global health
priority. There has been a tremendous effort to decipher underlying mechanisms …

Management of pneumonia in critically ill patients

C Cillóniz, A Torres, MS Niederman - bmj, 2021 - bmj.com
Severe pneumonia is associated with high mortality (short and long term), as well as
pulmonary and extrapulmonary complications. Appropriate diagnosis and early initiation of …

Updates on community acquired pneumonia management in the ICU

GB Nair, MS Niederman - Pharmacology & therapeutics, 2021 - Elsevier
While the world is grappling with the consequences of a global pandemic related to SARS-
CoV-2 causing severe pneumonia, available evidence points to bacterial infection with …

[HTML][HTML] Expert consensus on the monitoring and treatment of sepsis-induced immunosuppression

F Pei, RQ Yao, C Ren, S Bahrami, TR Billiar… - Military Medical …, 2022 - Springer
Emerged evidence has indicated that immunosuppression is involved in the occurrence and
development of sepsis. To provide clinical practice recommendations on the immune …

[HTML][HTML] Targeting intracellular oncoproteins with dimeric IgA promotes expulsion from the cytoplasm and immune-mediated control of epithelial cancers

S Biswas, G Mandal, CM Anadon, RA Chaurio… - Immunity, 2023 - cell.com
Dimeric IgA (dIgA) can move through cells via the IgA/IgM polymeric immunoglobulin
receptor (PIGR), which is expressed mainly on mucosal epithelia. Here, we studied the …

[HTML][HTML] XueBiJing injection versus placebo for critically ill patients with severe community-acquired pneumonia: a randomized controlled trial

Y Song, C Yao, Y Yao, H Han, X Zhao, K Yu… - Critical care …, 2019 - journals.lww.com
Objectives: To investigate whether XueBiJing injection improves clinical outcomes in
critically ill patients with severe community-acquired pneumonia. Design: Prospective …

[PDF][PDF] S3-leitlinie sepsis–prävention, diagnose, therapie und nachsorge

FM Brunkhorst, MA Weigand, M Pletz… - 2020 - publications.goettingen-research …
BeieinerSepsishandeltessichumeinelebens… Organdysfunktion ausgelöst durch eine
Infektion, die mit einer Regulationsstörung beim Wirt einhergeht. Ähnlich wie bei …