Body temperature regulation is a fundamental homeostatic function that is governed by the
central nervous system in homeothermic animals, including humans. The central …

Central neural circuits orchestrate a homeostatic repertoire to maintain body temperature
during environmental temperature challenges and to alter body temperature during the …

Immediate‐early genes (IEG) are powerful tools for identifying activated neurosecretory
neurones and extended circuits that affect neuroendocrine functions. The generally …

Leptin regulates body weight in mice by decreasing appetite and increasing sympathetic
nerve activity (SNA), which increases energy expenditure in interscapular brown adipose …

Leptin signals the repletion of fat stores, acting in the CNS to permit energy utilization by a
host of autonomic and neuroendocrine processes and to decrease feeding. While much …

Objective Leptin responsive neurons play an important role in energy homeostasis,
controlling specific autonomic, behavioral, and neuroendocrine functions. We have …

Brown adipose tissue (BAT) thermogenesis is critical to maintain homoeothermia and is
centrally controlled via sympathetic outputs. Body temperature and BAT activity also impact …

Intense stress and fear have long been known to give rise to a suppression of pain termed
“stress-induced analgesia”, mediated by brainstem pain-modulating circuitry, including pain …

Psychological stress‐induced hyperthermia is a fundamental autonomic response in
mammals. However, the central circuitry underlying this stress response is poorly …

We recently showed that transcranial alternating current stimulation of the dorsolateral
prefrontal cortex modulates spontaneous bursts of muscle sympathetic nerve activity, heart …