Electrospun amorphous solid dispersions of poorly water-soluble drugs: A review

DG Yu, JJ Li, GR Williams, M Zhao - Journal of controlled release, 2018 - Elsevier
The development of oral dosage forms for poorly water-soluble active pharmaceutical
ingredients (APIs) is a persistent challenge. A range of methods has been explored to …

Current trends and future perspectives of solid dispersions containing poorly water-soluble drugs

CLN Vo, C Park, BJ Lee - European journal of pharmaceutics and …, 2013 - Elsevier
Over 40% of active pharmaceutical ingredients (API) in development pipelines are poorly
water-soluble drugs which limit formulation approaches, clinical application and …

A review of emerging technologies enabling improved solid oral dosage form manufacturing and processing

MS Arshad, S Zafar, B Yousef, Y Alyassin, R Ali… - Advanced drug delivery …, 2021 - Elsevier
Tablets are the most widely utilized solid oral dosage forms because of the advantages of
self-administration, stability, ease of handling, transportation, and good patient compliance …

Spherical mesoporous silica nanoparticles for loading and release of the poorly water-soluble drug telmisartan

Y Zhang, Z Zhi, T Jiang, J Zhang, Z Wang… - Journal of Controlled …, 2010 - Elsevier
The purpose of this study was to develop mesoporous silica nanoparticles (MSNs) loaded
with a poorly water-soluble drug, intended to be orally administered, able to improve the …

Response and regulation of the microenvironment based on hollow structured drug delivery systems

D Zhao, Y Wei, J Xiong, C Gao… - Advanced Functional …, 2023 - Wiley Online Library
Hollow structured materials with easily modifiable surfaces and enclosed interior spaces
have emerged as the most promising candidates in drug delivery systems (DDS). With …

Chitosan coated magnetic nanoparticles as carriers of anticancer drug Telmisartan: pH-responsive controlled drug release and cytotoxicity studies

RP Dhavale, RP Dhavale, SC Sahoo, P Kollu… - Journal of Physics and …, 2021 - Elsevier
Chitosan, a natural, hydrophilic and biodegradable polymer was grafted on Fe 3 O 4
magnetic nanoparticles (MNPs) and used as a carrier of poorly water-soluble anticancer …

[PDF][PDF] RETRACTED ARTICLE: Potential of solid dispersions to enhance solubility, bioavailability, and therapeutic efficacy of poorly water-soluble drugs: newer …

S Alshehri, SS Imam, A Hussain, MA Altamimi… - Drug …, 2020 - Taylor & Francis
Abstract We, the Editors and Publisher of Drug Delivery have retracted the following article:
Sultan Alshehri, Syed Sarim Imam, Afzal Hussain, Mohammad A. Altamimi, Nabil K …

Mesoporous silica nanoparticles for increasing the oral bioavailability and permeation of poorly water soluble drugs

Y Zhang, J Wang, X Bai, T Jiang, Q Zhang… - Molecular …, 2012 - ACS Publications
We investigate the effects of spherical mesoporous silica nanoparticles (MSNs) as an oral
drug delivery system to improve the oral bioavailability of the model drug telmisartan (TEL) …

[HTML][HTML] Fabrication of intragastric floating, controlled release 3D printed theophylline tablets using hot-melt extrusion and fused deposition modeling

BR Giri, ES Song, J Kwon, JH Lee, JB Park, DW Kim - Pharmaceutics, 2020 - mdpi.com
This work presents a novel approach for producing gastro-retentive floating tablets (GRFT)
by coupling hot-melt extrusion (HME) and fused deposition three-dimensional printing …

Hot-melt extruded amorphous solid dispersion for solubility, stability, and bioavailability enhancement of telmisartan

BR Giri, J Kwon, AQ Vo, AM Bhagurkar, S Bandari… - Pharmaceuticals, 2021 - mdpi.com
Telmisartan (TEL, an antihypertensive drug) belongs to Class II of the Biopharmaceutical
Classification System (BCS) because of its poor aqueous solubility. In this study, we …