WHO global research priorities for antimicrobial resistance in human health

S Bertagnolio, Z Dobreva, CM Centner, ID Olaru… - The Lancet …, 2024 - thelancet.com
The WHO research agenda for antimicrobial resistance (AMR) in human health has
identified 40 research priorities to be addressed by the year 2030. These priorities focus on …

A scoping review describes methods used to identify, prioritize and display gaps in health research

L Nyanchoka, C Tudur-Smith, V Iversen… - Journal of clinical …, 2019 - Elsevier
Abstract Background and Objectives Different methods to examine research gaps have
been described, but there are still no standard methods for identifying, prioritizing, or …

Tuberculosis-HIV co-infection: progress and challenges after two decades of global antiretroviral treatment roll-out

E Letang, J Ellis, K Naidoo, EC Casas… - Archivos de …, 2020 - Elsevier
Despite wide antiretroviral scale-up during the past two decades resulting in declining new
infections and mortality globally, HIV-associated tuberculosis remains as a major public …

[HTML][HTML] Preventing the spread of multidrug-resistant tuberculosis and protecting contacts of infectious cases

GJ Fox, HS Schaaf, A Mandalakas, E Chiappini… - Clinical Microbiology …, 2017 - Elsevier
Prevention of multidrug-resistant and extensively drug-resistant tuberculosis (MDR/XDR-TB)
is a top priority for global TB control, given the need to limit epidemic spread and …

Adverse drug reactions during drug-resistant TB treatment in high HIV prevalence settings: a systematic review and meta-analysis

K Schnippel, C Firnhaber, R Berhanu… - Journal of …, 2017 - academic.oup.com
Objectives: To estimate the prevalence of adverse drug reactions or events (ADR) during
drug-resistant TB (DR-TB) treatment in the context of settings with high HIV prevalence (at …

[HTML][HTML] Global knowledge gaps on antimicrobial resistance in the human health sector: A scoping review

RL Hamers, Z Dobreva, A Cassini, A Tamara… - International Journal of …, 2023 - Elsevier
Objectives To identify and summarize existing global knowledge gaps on antimicrobial
resistance (AMR) in human health, focusing on the World Health Organization (WHO) …

[HTML][HTML] Insignificant difference in culture conversion between bedaquiline-containing and bedaquiline-free all-oral short regimens for multidrug-resistant tuberculosis

L Fu, T Weng, F Sun, P Zhang, H Li, Y Li, Q Yang… - International Journal of …, 2021 - Elsevier
Background Multidrug-resistant tuberculosis (MDR-TB) patients have been suffering long,
ineffective, and toxic treatment until short-course injectable-free regimens emerged …

Risk factors for mortality among patients diagnosed with multi-drug resistant tuberculosis in Uganda-a case-control study

E Kizito, J Musaazi, K Mutesasira… - BMC infectious …, 2021 - Springer
Abstract Background The World Health Organization (WHO) End TB strategy aims to reduce
mortality due to tuberculosis (TB) to less than 5% by 2035. However, mortality due to …

Recently developed drugs for the treatment of drug-resistant tuberculosis: a research and development case study

C Perrin, K Athersuch, G Elder, M Martin… - BMJ Global …, 2022 - gh.bmj.com
Two drugs with novel mechanisms of action, the diarylquinoline bedaquiline and the
nitroimidazole delamanid—as well as pretomanid from the same class of drugs as …

Latent tuberculous infection in household contacts of multidrug-resistant and newly diagnosed tuberculosis

GJ Fox, NT Anh, NV Nhung, NT Loi… - … of Tuberculosis and …, 2017 - ingentaconnect.com
BACKGROUND: Differences in the prevalence of latent tuberculous infection (LTBI) and
tuberculosis (TB) disease among contacts of patients with multidrug-resistant TB (MDR-TB) …