[HTML][HTML] A comprehensive review on Pueraria: Insights on its chemistry and medicinal value

S Wang, S Zhang, S Wang, P Gao, L Dai - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Pueraria species are listed in the Chinese Pharmacopeia and are being used for the
treatment of various health ailments and in protecting health. Puerarin, a chemotaxonomic …

Antioxidant effect of flavonoids present in Euterpe oleracea Martius and neurodegenerative diseases: A literature review

NKS de Oliveira, MRS Almeida… - … System Agents in …, 2019 - ingentaconnect.com
Introduction: Neurodegenerative diseases (NDDs) are progressive, directly affecting the
central nervous system (CNS), the most common and recurrent are Alzheimer's disease …

Puerarin suppresses MPP+/MPTP-induced oxidative stress through an Nrf2-dependent mechanism

X Li, J Zhang, X Zhang, M Dong - Food and Chemical Toxicology, 2020 - Elsevier
In this study, we hypothesized that anti-parkinsonian effect of puerarin is attributable to its
antioxidant properties via Nrf2-dependent glutathione (GSH) biosynthesis mechanism …

Phytoestrogen coumestrol selectively inhibits monoamine oxidase-a and amyloid β self-aggregation

SH Seong, BR Kim, ML Cho, TS Kim, S Im, S Han… - Nutrients, 2022 - mdpi.com
Pueraria lobata leaves contain a variety of phytoestrogens, including flavonoids,
isoflavonoids, and coumestan derivatives. In this study, we aimed to identify the active …

Stable isotope labeling derivatization and magnetic dispersive solid phase extraction coupled with UHPLC-MS/MS for the measurement of brain neurotransmitters in …

XE Zhao, Y He, S Zhu, Y Xu, J You, Y Bai, H Liu - Analytica chimica acta, 2019 - Elsevier
Synchronous measurement of brain neurotransmitters and blood drug metabolism by dual
sites in vivo microdialysis can provide very important information for several neurological …

Astragalus polysaccharides protect renal function and affect the TGF-β/Smad signaling pathway in streptozotocin-induced diabetic rats

X Meng, M Wei, D Wang, X Qu… - Journal of …, 2020 - journals.sagepub.com
Objectives The objective was to observe the effects of Astragalus polysaccharides on
diabetes and on regulation of the TGF-β/Smad signaling pathway. Methods A type 2 diabetic …

Downregulation of Nogo-B ameliorates cerebral ischemia/reperfusion injury in mice through regulating microglia polarization via TLR4/NF-kappaB pathway

P Gong, HY Jia, R Li, Z Ma, M Si, C Qian, F Zhu… - Neurochemistry …, 2023 - Elsevier
Many studies have shown a close association between Nogo-B and inflammation-related
diseases. However, uncertainty does exist, regarding Nogo-B function in the pathological …

Puerarin relieved compression‐induced apoptosis and mitochondrial dysfunction in human nucleus pulposus mesenchymal stem cells via the PI3K/Akt pathway

D Huang, Y Peng, K Ma, X Qing, X Deng… - Stem Cells …, 2020 - Wiley Online Library
Puerarin (PUR), an 8‐C‐glucoside of daidzein extracted from Pueraria plants, is closely
related to autophagy, reduced reactive oxygen species (ROS) production, and anti …

Assessment of heavy metals contamination and human health risk assessment of the commonly consumed medicinal herbs in China

H Liu, J Tang, T Chen, P Zhu, D Sun… - Environmental Science and …, 2023 - Springer
This study investigates heavy metal contamination of commonly consumed medicinal herbs
and human health risks to the Chinese population arising from the consumption of herbs that …

Flavonoids: The use in mental health and related diseases

C Nicolucci, M Padovani, FC Rodrigues… - Natural Product …, 2024 - Taylor & Francis
Given the current increase in mental and neurological disorders, there is an urgent need to
develop alternative treatments for patients. Flavonoids exhibit diverse biological activities …