From classical to new generation approaches: An excursus of-omics methods for investigation of protein-protein interaction networks

I Iacobucci, V Monaco, F Cozzolino, M Monti - Journal of proteomics, 2021 - Elsevier
Functional Proteomics aims to the identification of in vivo protein-protein interaction (PPI) in
order to piece together protein complexes, and therefore, cell pathways involved in …

Phytochemical Profile of Capsicum annuum L. cv Senise, Incorporation into Liposomes, and Evaluation of Cellular Antioxidant Activity

C Sinisgalli, I Faraone, A Vassallo, C Caddeo… - Antioxidants, 2020 - mdpi.com
Overproduction of oxidants in the human body is responsible for oxidative stress, which is
associated with several diseases. High intake of vegetables and fruits can reduce the risk of …

Solanum aethiopicum L. from the Basilicata Region Prevents Lipid Absorption, Fat Accumulation, Oxidative Stress, and Inflammation in OA-Treated HepG2 and Caco …

L Lela, D Russo, F De Biasio, D Gorgoglione, A Ostuni… - Plants, 2023 - mdpi.com
Obesity is widely associated with intestine barrier impairment, nonalcoholic fatty liver
disease (NAFLD) outbreaks, oxidative stress, and inflammation. In a previous investigation …

Proteomic analysis of mucopolysaccharidosis IIIB mouse brain

V De Pasquale, M Costanzo, RA Siciliano, MF Mazzeo… - Biomolecules, 2020 - mdpi.com
Mucopolysaccharidosis IIIB (MPS IIIB) is an inherited metabolic disease due to deficiency of
α-N-Acetylglucosaminidase (NAGLU) enzyme with subsequent storage of undegraded …

The 75–99 C-Terminal Peptide of URG7 Protein Promotes α-Synuclein Disaggregation

J Dandurand, M Monné, V Samouillan, M Rosa… - International Journal of …, 2024 - mdpi.com
Up Regulation Gene seven (URG7) is the pseudogene 2 of the transporter ABCC6. The
translated URG7 protein is localized with its single transmembrane α-helix in the …

Sulodexide attenuates endoplasmic reticulum stress induced by myocardial ischaemia/reperfusion by activating the PI3K/Akt pathway

D Shen, R Chen, L Zhang, Z Rao… - Journal of cellular …, 2019 - Wiley Online Library
Acute myocardial ischaemia/reperfusion (MI/R) injury causes severe arrhythmias with a high
rate of lethality. Extensive research focus on endoplasmic reticulum (ER) stress and its …

CircZXDC promotes vascular smooth muscle cell transdifferentiation via regulating miRNA-125a-3p/ABCC6 in moyamoya disease

Y Liu, Y Huang, X Zhang, X Ma, X He, C Gan, X Zou… - Cells, 2022 - mdpi.com
Moyamoya disease (MMD) is an occlusive, chronic cerebrovascular disease affected by
genetic mutation and the immune response. Furthermore, vascular smooth muscle cells …

New Insight on the Bioactivity of Solanum aethiopicum Linn. Growing in Basilicata Region (Italy): Phytochemical Characterization, Liposomal Incorporation, and …

I Faraone, L Lela, M Ponticelli, D Gorgoglione… - Pharmaceutics, 2022 - mdpi.com
Food extract's biological effect and its improvement using nanotechnologies is one of the
challenges of the last and the future decades; for this reason, the antioxidant effect of scarlet …

[HTML][HTML] Neuroprotective Effect of Antiapoptotic URG7 Protein on Human Neuroblastoma Cell Line SH-SY5Y

I Nigro, R Miglionico, M Carmosino, A Gerbino… - International Journal of …, 2023 - mdpi.com
Up-regulated Gene clone 7 (URG7) is a protein localized in the endoplasmic reticulum (ER)
and overexpressed in liver cells upon hepatitis B virus (HBV) infection. Its activity has been …

Two novel precursors of the hiv-1 protease inhibitor darunavir target the upr/proteasome system in human hepatocellular carcinoma cell line hepg2

R Rinaldi, R Miglionico, I Nigro, R D'Orsi… - Cells, 2021 - mdpi.com
Background: Several pre-clinical and clinical reports suggest that HIV-1 protease inhibitors,
in addition to the antiretroviral properties, possess pleiotropic pharmacological effects …