In type 2 diabetes mellitus, hepatic insulin resistance is intricately associated with oxidative
stress and inflammation. Nonetheless, the lack of therapeutic interventions directly targeting …

Vinylpyrazoles, also known as pyrazolyl olefins, are interesting motifs in organic chemistry
but have been overlooked. This review describes the properties and synthetic routes of …

The review presents extensive data (from the author's work and the literature) on the
stereochemical structure of functionalized organophosphorus azoles (pyrroles, pyrazoles …

Glycogen phosphorylase (GP) is the rate-determining enzyme in the glycogenolysis
pathway. Glioblastoma (GBM) is amongst the most aggressive cancers of the central …

Abstract One new flavan (1), besides four known flavanones (2–5), was isolated from the
aerial parts of Cyperus conglomeratus Rottb. Their structures were established by …

Artur Silva's research group has a long history in the field of medicinal chemistry. The
development of new synthetic methods for oxygen (mostly polyphenols, eg, 2-and 3 …

India and Ethiopia employ Guizotia abyssinica (niger plant) as a source of edible vegetable
oil. Previous studies have documented the niger plant's antioxidant properties and dietary …

In patients with type 2 diabetes mellitus (DM), excessive gluconeogenesis is considered a
major contributor to hyperglycemia. Therefore, targeting fructose 1, 6‐bisphosphatase …

Background: Owing to the chronic nature of Type 2 diabetes mellitus, antidiabetic drugs
must have long-lasting efficacy. Compound 1 has a good inhibitory effect on acute …

Glycogen phosphorylase (GP) is a rate-limiting allosteric enzyme in the glycogenolysis
pathway that contributes to hyperglycemia in type 2 diabetes (T2D). Hence, researchers …