Simple Summary Cell migration is an essential process from embryogenesis to cell death.
This is tightly regulated by numerous proteins that help in proper functioning of the cell. In …

Altered energy metabolism is one of the hallmarks of tumorigenesis and essential for
fulfilling the high demand for metabolic energy in a tumor through accelerating glycolysis …

Metabolic reprogramming is commonly recognized as one important hallmark of cancers.
Cancer cells present significant alteration of glucose metabolism, oxidative phosphorylation …

Background: Breast cancer (BC) is the most common cancer in women. The incidence and
morbidity of BC are expected to rise rapidly. The stage at which BC is diagnosed has a …

Gastrointestinal (GI) cancers, as the most common human malignancies are always
considered one of the most important health challenges in the world. Late diagnosis in …

LncRNAs play a pivotal role in the regulation of epigenetic modification, cell cycle,
differentiation, proliferation, migration and other physiological activities. In particular …

Transforming growth factor β (TGF-β) family members play an extensive role in cellular
communication that orchestrates both early development and adult tissue homeostasis …

Metabolic rewiring offers novel therapeutic opportunities in cancer. Until recently, there was
scant information regarding soft tissue sarcomas, due to their heterogeneous tissue origin …

Cancer cells exhibit distinct metabolic characteristics that employ glycolysis to provide
energy and intermediary metabolites. This aberrant metabolic phenotype favors cancer …

Background In this review, we describe how the cytoskeletal protein Merlin, encoded by the
Neurofibromin 2 (NF2) gene, orchestrates developmental signaling to ensure normal …