Epidermal growth factor receptor (EGFR) is an oncogenic drug target and plays a critical role
in several cellular functions including cancer cell growth, survival, proliferation …

The explosive growth of single-molecule techniques is transforming our understanding of
biology, helping to develop new physics inspired by emergent biological processes, and …

Decrypting the dynamics of receptor dimerization on cell membranes bears great
importance in identifying the mechanisms regulating diverse cellular activities. In this regard …

Na+/taurocholate cotransporting polypeptide (NTCP) is a member of the solute carrier (SLC)
family 10 transporters (gene symbol SLC10A1) and is responsible for the sodium-dependent …

BY-kinases (for bacterial tyrosine kinases) constitute a family of protein tyrosine kinases that
are highly conserved in the bacterial kingdom and occur most commonly as essential …

Background: Plasmolipin (PLLP) is a membrane protein located in lipid rafts that participates
in the formation of myelin. It is also implicated in many pathologies, such as neurological …

Overexpression of receptor tyrosine kinases (RTKs) or binding to ligands can lead to the
formation of specific unliganded and liganded RTK dimers, and these two RTK dimers are …

Oncogenic mutations within the EGFR kinase domain are well-established driver mutations
in non–small cell lung cancer (NSCLC). Small-molecule tyrosine kinase inhibitors (TKIs) …

Epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase (RTK) that is
upregulated in aggressive triple-negative breast cancer (TNBC). Ligands such as EGF, TGF …

The structural basis of the activation and internalization of EGF receptors (EGFR) is still a
matter of debate despite the importance of this target in cancer treatment. Whether agonists …