Neurofibromatosis type 1 is a rare neurogenetic syndrome, characterized by pigmentary
abnormalities, learning and social deficits, and a predisposition for benign and malignant …

Protein phosphorylation affects conformational change, interaction, catalytic activity, and
subcellular localization of proteins. Because the post-modification of proteins regulates …

Despite available targeted treatments for the disease, drug-resistant chronic lymphocytic
leukemia (CLL) poses a clinical challenge. The objective of this study is to examine whether …

The mechanism underlying acute kidney injury (AKI) and AKI-to-Chronic kidney disease
(CKD) transition remains unclear, but mitochondrial dysfunction may be a key driving factor …

ABSTRACT Epstein-Barr virus (EBV)-encoded miRNAs within the BamHI-A rightward
transcript (BART) region are abundantly expressed in EBV-associated gastric cancer …

Preeclampsia (PE) is associated with maternal and fetal perinatal morbidity and mortality,
which brings tremendous suffering and imposes an economic burden worldwide. The failure …

Purpose Therapy resistance is the principal obstacle to achieving cures in cancer patients
and its successful tackling requires a deep understanding of the resistance mediators …

The renal interstitial fibrosis contributes to the progression and deterioration of diabetic
nephropathy (DN). Long noncoding RNA taurine-up-regulated gene 1 (TUG1) in kidneys …

Acute myeloid leukemia (AML) is an aggressive and heterogeneous hematologic
malignancy. In elderly patients, AML incidence is high and has a poor prognosis due to a …

HNRNPA2B1, an RNA-binding protein, plays a key role in primary microRNA processing,
alternative splicing, mRNA metabolism and transport. Interestingly, hnRNPA2B1 also works …