The Keap1/Nrf2/ARE system is a central defensive mechanism against oxidative stress
which plays a key role in the pathogenesis and progression of many diseases. Nrf2 is a …

Acute pancreatitis (AP), as a common cause of clinical acute abdomen, often leads to multi-
organ damage. In the process of severe AP, the lungs and intestines are the most easily …

Rationale: Acute pancreatitis (AP) is a serious acute condition affecting the abdomen and
shows high morbidity and mortality rates. Its global incidence has increased in recent years …

Background: One of the most common co-morbidities, that often leads to death, associated
with acute pancreatitis (AP) is represented by acute lung injury (ALI). While many aspects of …

Exogenous antioxidant materials mimicking endogenous antioxidant systems are commonly
used for the treatment of oxidative stress-induced injuries. Thus, artificial enzymes have …

Severe acute pancreatitis (SAP) is a severe acute abdominal disease. Recent evidence
shows that intestinal homeostasis is essential for the management of acute pancreatitis …

Borneol is a commonly used flavouring substance in traditional Chinese medicine, which
possesses several pharmacological activities including analgesic, antiinflammatory, and …

Oxidative tissue injury and inflammatory responses play major roles in cardiovascular
diseases and heart failure. Visnagin (VIS) is a natural bioactive component of Ammi visnaga …

Background. Danshen (Salvia miltiorrhiza Bunge) and its main active component
Tanshinone IIA (TSA) are clinically used in China. However, the effects of TSA on acute …

The metabolite profiling associated with the antioxidant potential of Amazonian fruits
represents an important step to the bioactive compound′ s characterization due to the large …